Issue 17, 2018
From the journal:

RSC Advances

White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation†

Jiamei Liang,ab   Pan Wu,ab   Chunyan Tan ORCID logo *ab  and  Yuyang Jiangbc  

* Corresponding authors

a Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China

b The State Key Laboratory of Chemical Oncogenomics, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China
E-mail: tancy@sz.tsinghua.edu.cn
Tel: +86-755-26036533

c School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, P. R. China

Abstract

A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway.

Graphical abstract: White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

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Article information

DOI
https://doi.org/10.1039/C8RA00774H
Article type
Paper
Submitted
25 janv. 2018
Accepted
25 févr. 2018
First published
01 mars 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 9218-9222

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White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

J. Liang, P. Wu, C. Tan and Y. Jiang, RSC Adv., 2018, 8, 9218 DOI: 10.1039/C8RA00774H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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