Mesoporous silica nanoparticles in recent photodynamic therapy applications

Sumeyra Bayir; Alexandre Barras; Rabah Boukherroub; Sabine Szunerits; Laurence Raehm; Sébastien Richeter; Jean-Olivier Durand

doi:10.1039/C8PP00143J

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Mesoporous silica nanoparticles in recent photodynamic therapy applications

Sumeyra Bayir,^ac Alexandre Barras,

^b Rabah Boukherroub,

^b Sabine Szunerits,

^b Laurence Raehm,^a Sébastien Richeter^a and Jean-Olivier Durand

*^a

Author affiliations

* Corresponding authors

^a Institut Charles Gerhardt Montpellier, UMR 5253, CNRS-UM-ENSCM, Université de Montpellier, Place Eugène Bataillon 34095, Montpellier cedex 05, France
E-mail: durand@umontpellier.fr

^b Univ. Lille, CNRS, Centrale Lille, ISEN, Univ. Valenciennes, UMR 8520 – IEMN, F-59000 Lille, France

^c Department of Chemistry, Gebze Technical University, Kocaeli 41400, Turkey

Abstract

In this review, the use of mesoporous silica nanoparticles for photodynamic therapy (PDT) applications is described for the year 2017. Since the pioneering work in 2009, nanosystems involving mesoporous silica nanoparticles have gained in complexity with a sophisticated core–shell system able to perform multi-imaging and multi-therapies, not only for cancer diseases but also for anti-microbial therapy, atherosclerosis, or Alzheimer disease. Near-infrared, excitation light based on up-converting systems, X-rays or persistent luminescent systems are described for deeper tissue treatments.

This article is part of the themed collections: Nano- and Molecular Engineering of Photosensitisers and 2018 Perspective article collection

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DOI: https://doi.org/10.1039/C8PP00143J
Article type: Perspective
Submitted: 05 avr. 2018
Accepted: 02 juil. 2018
First published: 06 juil. 2018

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Photochem. Photobiol. Sci., 2018,17, 1651-1674

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Mesoporous silica nanoparticles in recent photodynamic therapy applications

S. Bayir, A. Barras, R. Boukherroub, S. Szunerits, L. Raehm, S. Richeter and J. Durand, Photochem. Photobiol. Sci., 2018, 17, 1651 DOI: 10.1039/C8PP00143J

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Photochemical & Photobiological Sciences

Mesoporous silica nanoparticles in recent photodynamic therapy applications

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Mesoporous silica nanoparticles in recent photodynamic therapy applications

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