Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery

Yincheng Chang; Chenxi Hou; Jingli Ren; Xiaoting Xin; Yuxin Pei; Yuchao Lu; Shoupeng Cao; Zhichao Pei

doi:10.1039/C6CC03637F

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Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery†

Yincheng Chang,‡^a Chenxi Hou,‡^a Jingli Ren,^a Xiaoting Xin,^a Yuxin Pei,*^a Yuchao Lu,^a Shoupeng Cao^a and Zhichao Pei*^a

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* Corresponding authors

^a Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Science, Northwest A&F University, Yangling, Shaanxi 712100, People's Republic of China
E-mail: peiyx@nwafu.edu.cn, peizc@nwafu.edu.cn
Fax: +86 2987092769
Tel: +86 2987091196

Abstract

Supramolecular vesicles based on the host–guest complexation of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative have been constructed, which showed dual-responsiveness and cancer cells targetability resulting from its ferrocenecarboxylic acid units and galactose units, respectively. This work provides a good example for the construction of multifunctional nanocarriers for targeted drug delivery.

This article is part of the themed collection: Host–guest chemistry

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Article information

DOI: https://doi.org/10.1039/C6CC03637F
Article type: Communication
Submitted: 01 mai 2016
Accepted: 24 juin 2016
First published: 24 juin 2016

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Chem. Commun., 2016,52, 9578-9581

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Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery

Y. Chang, C. Hou, J. Ren, X. Xin, Y. Pei, Y. Lu, S. Cao and Z. Pei, Chem. Commun., 2016, 52, 9578 DOI: 10.1039/C6CC03637F

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Chemical Communications

Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery†

Abstract

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Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery

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