Issue 23, 2013
From the journal:

Chemical Communications

Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay†

Richard C. Knighton,a   Mark R. Sambrook,b   Jack C. Vincent,b   Simon A. Smith,b   Christopher J. Serpell,a   James Cookson,c   Matthew S. Vickersa  and  Paul D. Beer*a  

* Corresponding authors

a Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, UK
E-mail: paul.beer@chem.ox.ac.uk
Fax: +44 (0)1865 272960
Tel: +44 (0)1865 285182

b Detection Department, Dstl Porton Down, Salisbury, UK
E-mail: m.sambrook@dstl.gov.uk
Tel: +44 (0)1980 614301

c Johnson Matthey Technol Ctr, Reading RG4 9NH, Berks, England, UK

Abstract

The dansyl fluorophore ligated to gold nanoparticles via imidazole and amine groups affords conjugates capable of detecting micromolar concentrations of the chemical warfare agent sulfur mustard by a fluorescence switching ‘ON’ displacement assay.

Graphical abstract: Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay

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Article information

DOI
https://doi.org/10.1039/C3CC39105A
Article type
Communication
Submitted
20 déc. 2012
Accepted
06 févr. 2013
First published
07 févr. 2013

Chem. Commun., 2013,49, 2293-2295

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Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay

R. C. Knighton, M. R. Sambrook, J. C. Vincent, S. A. Smith, C. J. Serpell, J. Cookson, M. S. Vickers and P. D. Beer, Chem. Commun., 2013, 49, 2293 DOI: 10.1039/C3CC39105A

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