Issue 18, 2001

Identification of Tyr58 as the proton donor in the aspartate-α-decarboxylase reaction

Abstract

The decarboxylation of L-aspartate by E. coliL-aspartate-α-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.

Article information

Article type
Communication
Submitted
10 juil. 2001
Accepted
30 juil. 2001
First published
29 août 2001

Chem. Commun., 2001, 1760-1761

Identification of Tyr58 as the proton donor in the aspartate-α-decarboxylase reaction

S. A. Saldanha, L. M. Birch, M. E. Webb, B. K. Nabbs, F. von Delft, A. G. Smith and C. Abell, Chem. Commun., 2001, 1760 DOI: 10.1039/B106090M

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