Issue 17, 2018

Research progresses on the functional polypeptides in the detection and imaging of breast cancer

Abstract

Breast cancer is a serious threat to the health of women all over the world. The precise diagnosis and treatment of breast cancer are of great importance to control the development of breast cancer as well as to improve survival rates of the patients. Nowadays, polypeptides are widely applied in breast cancer-related research, benefiting from lower immunogenicity, better biodegradability, higher penetration, and easier synthesis and modification. In this review, we have summarized recent applications of functional polypeptides in the detection and imaging of breast cancer, in which polypeptides work not only as a recognition element and signal source for detecting and imaging breast tumours, but also a building block and a therapeutic drug to assist image-guided treatment of breast cancer.

Graphical abstract: Research progresses on the functional polypeptides in the detection and imaging of breast cancer

Article information

Article type
Review Article
Submitted
22 sept. 2017
Accepted
25 oct. 2017
First published
25 oct. 2017

J. Mater. Chem. B, 2018,6, 2510-2523

Research progresses on the functional polypeptides in the detection and imaging of breast cancer

J. Zhao, H. Chen, Y. Tang, H. Chen, G. Chen, Y. Yin and G. Li, J. Mater. Chem. B, 2018, 6, 2510 DOI: 10.1039/C7TB02541F

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