Themed collection Journal of Materials Chemistry B HOT Papers
Optical imaging probes for selective detection of butyrylcholinesterase
Butyrylcholinesterase (BChE) is a human serine hydrolase, which plays critical roles in various physiological and pathological states. Here, we summarized the optical probes that can selectively monitor the BChE activity in different biological models.
J. Mater. Chem. B, 2024,12, 1149-1167
https://doi.org/10.1039/D3TB02468G
Ni@TiO2 nanoribbon array electrode for high-efficiency non-enzymatic glucose biosensing
A Ni nanoparticle-decorated TiO2 nanoribbon array on a Ti plate serves as a highly efficient electrode for non-enzymatic glucose biosensing in alkaline environments.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01721H
Enhancing spleen-targeted mRNA delivery with branched biodegradable tails in lipid nanoparticles
Ionizable lipids with branched tails enhance the selective mRNA delivery to spleen, particularly to antigen-presenting cells.
J. Mater. Chem. B, 2024,12, 8062-8066
https://doi.org/10.1039/D4TB00960F
Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment
A novel drug delivery system hitchhiking albumin as a drug carrier with tuneable redox-responsive drug release.
J. Mater. Chem. B, 2024,12, 6563-6569
https://doi.org/10.1039/D4TB00751D
Bioinspired triple-layered membranes for periodontal guided bone regeneration applications
The combination bio-inspired nacre-like structure with biocompatible raw materials leads to mechanically strong and robust barrier membranes with improved periodontal guided bone regeneration performance.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01658K
Simultaneous detection of breast cancer biomarkers HER2 and miRNA-212 based on duplex-specific nuclease signal amplification
Simultaneous analysis of breast cancer biomarkers HER2 and miRNA-21 based on DSN.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01845A
Broad-spectrum degradation of fluoroquinolone antibiotics by Hemin-His-Fe nanozymes with peroxidase-like activity
A novel biomimetic peroxidase nanozymes named Hemin-His-Fe (HHF)-peroxidase nanozyme was synthesized for the broad-spectrum degradation of fluoroquinolone antibiotics.
J. Mater. Chem. B, 2024,12, 8647-8654
https://doi.org/10.1039/D4TB00508B
Development of a urea-bond cleavage reaction induced by nitric oxide for its fluorescence imaging
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01462F
Spontaneous assembly of a class of small molecule prodrugs directed by SN38
Conjugating SN38 with small hydrophilic molecules via a biodegradable linker results in small molecule self-assembling prodrugs that form well-defined nanofibers with varying surface charges in water.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01429D
Engineered Macrophages-Derived Exosomes by Click Chemistry for Treatment of osteomyelitis
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01346H
In situ biocatalytic ATP regulated, transient supramolecular polymerization
This work shows the biocatalytic ATP regulation induced self-assembly of one-dimensional nanostructures akin to the self-assembly process of actin. Coupled ATP generation and ATP hydrolysis render the supramolecular aggregates transient.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01558D
A biodegradable calcium sulfite nanoreactor for pH triggered gas therapy in combination with chemotherapy
A biodegradable HCSL nanoreactor was constructed by the in situ encapsulation of 10-hydroxycamptothecin into a calcium sulfite nanocarrier and then modifying liposomes for tumor-enhanced SO2 gas therapy in combination with chemotherapy.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01468E
Fabrication of conjugated polymers with aggregation-induced near-infrared-II emission for efficient phototheranostics
NIR-II conjugated polymers with typical AIE characteristics have been fabricated for bight NIR-II fluorescence imaging guided photothermal therapy of cancer.
J. Mater. Chem. B, 2024,12, 8383-8388
https://doi.org/10.1039/D4TB01198H
Study of transient absorption spectroscopy of a D–π–A structure aggregation-induced emission luminogen and its photodynamic therapy application
Transient absorption spectroscopy has revealed that AIEgens exhibit a more rapid and facile excited-state molecular motion in the solution state compared to the aggregate state, implying the predominance of nonradiative decay in the solution state.
J. Mater. Chem. B, 2024,12, 8349-8356
https://doi.org/10.1039/D4TB01175A
Designing thermoreversible gels for extended release of mosquito repellent
Inspired by the excellent substrate loading of drug-delivery gels, we design and develop thermoreversible physical gels with a gelling solvent solely composed of insect repellent that demonstrates mosquito repellency for more than half a year.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01384K
Chemo-photothermal therapy of bacterial infections using metal–organic framework-integrated polymeric network coatings
A multifunctional MOF-integrated polymeric coating was deposited on the substrate surface in a one-step process to eradicate the adhered bacteria via combined antibacterial chemotherapeutic and photothermal therapeutic effects.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00237G
A spermine-responsive supramolecular chemotherapy system constructed from a water-soluble pillar[5]arene and a diphenylanthracene-containing amphiphile for precise chemotherapy
Stimuli-responsive supramolecular chemotherapy, particularly in response to cancer biomarkers, has emerged as a promising strategy to overcome the limitations associated with traditional chemotherapy.
J. Mater. Chem. B, 2024,12, 8099-8106
https://doi.org/10.1039/D4TB00668B
Compelling DNA intercalation through ‘anion–anion’ anti-coulombic interactions: boron cluster self-vehicles as promising anticancer agents
The amphiphilic anionic ferrabis(dicarbollide) boron-rich small molecule effectively penetrates the nucleus as a carrier-free drug and intercalates with ds-DNA base pairs, making it a promising candidate for multimodal cancer radiotherapy.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01177E
Matrix-degrading soft-nanoplatform with enhanced tissue penetration for amplifying photodynamic therapeutic efficacy of breast cancer
Herein, we successfully prepared matrix-degrading soft-nanocapsules with enhanced penetration ability for tumors, which effectively improves the photodynamic therapeutic efficacy.
J. Mater. Chem. B, 2024,12, 7837-7847
https://doi.org/10.1039/D4TB00894D
An integrated platform for decoding hydrophilic peptide fingerprints of hepatocellular carcinoma using artificial intelligence and two-dimensional nanosheets
A multifunctional platform integrating artificial intelligence, hydrophilic nanosheets, and MALDI-MS testing. This platform aims to achieve highly sensitive hydrophilic peptide fingerprints for accurate hepatocellular carcinoma diagnosis.
J. Mater. Chem. B, 2024,12, 7532-7542
https://doi.org/10.1039/D4TB00700J
Sprayable, thermosensitive hydrogels for promoting wound healing based on hollow, porous and pH-sensitive ZnO microspheres
Based on the antibacterial effects and adsorption of the porous ZnO microspheres, a thermosensitive hydrogel dressing containing CNPs and ZnO@CNPs was designed for wound healing applications.
J. Mater. Chem. B, 2024,12, 7519-7531
https://doi.org/10.1039/D4TB00961D
A polymeric 1H/19F dual-modal MRI contrast agent with a snowman-like Janus nanostructure
Magnetic resonance imaging (MRI) has emerged as a pivotal tool in contemporary medical diagnostics, offering non-invasive and high-resolution visualization of internal structures.
J. Mater. Chem. B, 2024,12, 7090-7102
https://doi.org/10.1039/D4TB00923A
Thermosensitive curcumin/silver/montmorillonite-F127 hydrogels with synergistic photodynamic/photothermal/silver ions antibacterial activity
The CAM-F hydrogel can achieve rapid microbial inactivation against E. coli and S. aureus. Based on Ag+, PDT, and PTT synergistic antibacterial properties, CAM-F hydrogels can effectively adhere to bacteria and destroy their cell membranes.
J. Mater. Chem. B, 2024,12, 6874-6885
https://doi.org/10.1039/D4TB00431K
In vitro and in vivo biocompatibility assessment of chalcogenide thermoelectrics as implants
This study conducted the first comprehensive in vitro and in vivo biocompatibility assessment of twelve typical sulfide compounds, identifying promising thermoelectric biomaterials and establishing a foundation for their application in biomedicine.
J. Mater. Chem. B, 2024,12, 6847-6855
https://doi.org/10.1039/D4TB00973H
Microenvironment-responsive release of Mg2+ from tannic acid decorated and multilevel crosslinked hydrogels accelerates infected wound healing
Microenvironment-responsive release of Mg2+ from tannic acid-decorated, multilevel crosslinked hydrogels with ROS scavenging, antibacterial, anti-inflammatory, and tissue regenerative properties for accelerated healing of infected wounds.
J. Mater. Chem. B, 2024,12, 6856-6873
https://doi.org/10.1039/D4TB01000K
Self-healing, antibiofouling and anticorrosion properties enabled by designing polymers with dynamic covalent bonds and responsive linkages
The combination of self-healing property and controlled release of corrosion inhibitor yield polymer coatings with excellent anticorrosion properties.
J. Mater. Chem. B, 2024,12, 6827-6839
https://doi.org/10.1039/D4TB00736K
A water-soluble luminescent tris(2,4,6-trichlorophenyl)methyl radical-carbazole dyad
Organic luminescent radicals are a new class of materials. New water-soluble tris(2,4,6-trichlorophenyl)methyl (TTM) radicals were synthesized, and potential as fluorescence and magnetic resonance imaging agent was investigated.
J. Mater. Chem. B, 2024,12, 6840-6846
https://doi.org/10.1039/D4TB00940A
Tough and elastic hydrogels based on robust hydrophobicity-assisted metal ion coordination for flexible wearable devices
A hydrogel-based flexible sensor based on hydrophobicity-assisted metal ion coordination is reported for human movement monitoring and physiological signal detection.
J. Mater. Chem. B, 2024,12, 6605-6616
https://doi.org/10.1039/D4TB00933A
Multifunctional protocatechuic acid–polyacrylic acid hydrogel adhesives for wound dressings
Illustration of the multifunctional hydrogel exhibiting excellent mechanical properties, adhesion, antibacterial and antioxidant activities, and wound healing capabilities.
J. Mater. Chem. B, 2024,12, 6617-6626
https://doi.org/10.1039/D4TB00425F
Metal–organic framework-interfaced ELISA probe enables ultrasensitive detection of extracellular vesicle biomarkers
The synthesis and application of microscale metal–organic framework (MOF)/enzyme composite particles as a novel detection probe to enhance the sensitivity of ELISA.
J. Mater. Chem. B, 2024,12, 6342-6350
https://doi.org/10.1039/D4TB00585F
A robust and biodegradable hydroxyapatite/poly(lactide-co-ε-caprolactone) electrospun membrane for dura repair
The robust and biodegradable hydroxyapatite/poly(lactide-co-ε-caprolactone) (nHA/PLCL) electrospun membrane demonstrated anti-adhesion, prevention of CSF leakage, and pro-dura reconstruction capacities.
J. Mater. Chem. B, 2024,12, 6117-6127
https://doi.org/10.1039/D4TB00863D
A flexible, stretchable and wearable strain sensor based on physical eutectogels for deep learning-assisted motion identification
A stretchable lignin-reinforced physical eutectogel was constructed and used as a wearable strain sensor, which displays promising potential in human motion detection and gesture recognition by combing with deep-learning techniques.
J. Mater. Chem. B, 2024,12, 6102-6116
https://doi.org/10.1039/D4TB00809J
Radioactive hybrid semiconducting polymer nanoparticles for imaging-guided tri-modal therapy of breast cancer
Radioactive hybrid semiconducting polymer nanoparticles are developed for imaging-guided photothermal–photodynamic–sonodynamic tri-modal therapy of breast cancer.
J. Mater. Chem. B, 2024,12, 6091-6101
https://doi.org/10.1039/D4TB00834K
Peptide nanovaccine conjugated via a retro-Diels–Alder reaction linker for overcoming the obstacle in lymph node penetration and eliciting robust cellular immunity
Nanovaccine conjugated via a retro-Diels–Alder reaction achieves lymph node deep penetration of antigens for enhancing vaccine efficacy.
J. Mater. Chem. B, 2024,12, 5848-5860
https://doi.org/10.1039/D4TB00674G
A ratiometric fluorescent probe revealing the abnormality of acetylated tau by visualizing polarity in Alzheimer's disease
A ratiometric fluorescent probe with high fluorescence efficiency in hydrophilic environment was developed. The probe not only tracked changes in cell polarity, but also found abnormal brain polarity in APP/PS1 mice compared to wild-type mice.
J. Mater. Chem. B, 2024,12, 5619-5627
https://doi.org/10.1039/D4TB00357H
Targeted inhibition of pyroptosis via a carbonized nanoinhibitor for alleviating drug-induced acute kidney injury
A carbonized nanoinhibitor derived from a small molecule pyroptosis inhibitor is constructed to ameliorate drug-induced acute kidney injury by inhibiting pyroptosis with a favorable kidney-targeting ability and high therapeutic efficacy.
J. Mater. Chem. B, 2024,12, 5609-5618
https://doi.org/10.1039/D4TB00382A
Dual delivery of carbon monoxide and doxorubicin using haemoglobin–albumin cluster: proof of concept for well-tolerated cancer therapy
The dual delivery of CO and DOX using HemoAct is a promising strategy as an anti-tumour agent to realise well-tolerated cancer therapy with minimal cardiotoxicity.
J. Mater. Chem. B, 2024,12, 5600-5608
https://doi.org/10.1039/D4TB00123K
Structure–activity relationships of aniline-based squaraines for distinguishable staining and bright two-photon fluorescence bioimaging in plant cells
Regulation effects of three aniline-based squaraines were investigated. The first expression of distinct tissue labelling and high-resolution 3D reconstruction in the onion and plant cells induced by the subtle structure changes was further evaluated.
J. Mater. Chem. B, 2024,12, 5350-5359
https://doi.org/10.1039/D4TB00400K
A dual-color ESIPT-based probe for simultaneous detection of hydrogen sulfide and hydrazine
An ESIPT-based dual-color fluorescent probe (BDM-DNP) can detect H2S and N2H4 in environmental and biological systems.
J. Mater. Chem. B, 2024,12, 5150-5156
https://doi.org/10.1039/D4TB00318G
Acceptor–donor–acceptor-type molecules with large electrostatic potential difference for effective NIR photothermal therapy
We explored a new way of utilizing the ESP difference to improve the molecular packing of (A–D–A) type molecules, and obtained a series of NIR PTAs with good PTT performance. The in vivo antitumor study demonstrates effective suppression of tumors.
J. Mater. Chem. B, 2024,12, 5140-5149
https://doi.org/10.1039/D4TB00187G
Enhancing antibacterial properties by regulating valence configurations of copper: a focus on Cu-carboxyl chelates
Enhancing the antibacterial properties by regulating valence configurations of copper: a focus on Cu-carboxyl chelates.
J. Mater. Chem. B, 2024,12, 5128-5139
https://doi.org/10.1039/D4TB00370E
Synthesis and characterization of a pH/temperature-dual responsive hydrogel with promising biocompatibility features for stimuli-responsive 5-FU delivery
The study focused on the fine refinement of PNIPAM-based materials, resulting in enhanced biocompatibility and drug loading for a smart hydrogel system with multi-responsive 5-FU release.
J. Mater. Chem. B, 2024,12, 5098-5110
https://doi.org/10.1039/D4TB00168K
Lysosomal-targeted fluorescent probe based pH regulating reactivity for tracking cysteine dynamics under oxidative stress
The ability to detect and visualize cellular events and associated biological analytes is essential for the understanding of their physiological and pathological functions.
J. Mater. Chem. B, 2024,12, 5157-5161
https://doi.org/10.1039/D4TB00478G
Micro-environment triple-responsive hyaluronic acid hydrogel dressings to promote antibacterial activity, collagen deposition, and angiogenesis for diabetic wound healing
pH/ROS/glucose triple-responsive OAH@TA hydrogel elicits controlled TA release, enhancing antibacterial, anti-inflammatory, and antioxidative properties to facilitate diabetic wound healing.
J. Mater. Chem. B, 2024,12, 4613-4628
https://doi.org/10.1039/D4TB00261J
Cancer nutritional-immunotherapy with NIR-II laser-controlled ATP release based on material repurposing strategy
Material repurposing is proposed where the performance of carbonyl iron powder (CIP), a nutritional intervention agent of iron supplement approved by the US FDA for iron deficiency anemia in clinic, was explored in anti-cancer treatment.
J. Mater. Chem. B, 2024,12, 4629-4641
https://doi.org/10.1039/D4TB00288A
A translocation fluorescent probe for analyzing cellular physiological parameters in neurological disease models
Different organelle-staining behaviors of OQ and PQ, and intracellular translocation of OQ caused by the changes of CMP and MMP.
J. Mater. Chem. B, 2024,12, 4398-4408
https://doi.org/10.1039/D4TB00557K
Tetramethylpyrazine-loaded electroconductive hydrogels promote tissue repair after spinal cord injury by protecting the blood–spinal cord barrier and neurons
The tetramethylpyrazine-loaded conductive hydrogel could diminish the breakdown of the blood–spinal cord barrier and protect against neuronal cell death to synergistically restore neurological functions post spinal cord injury.
J. Mater. Chem. B, 2024,12, 4409-4426
https://doi.org/10.1039/D3TB02160B
Cyaonoside A-loaded composite hydrogel microspheres to treat osteoarthritis by relieving chondrocyte inflammation
Drug-loaded composite hydrogel microspheres HAMA@Lipo@CyA (HLC) alleviate osteoarthritis by suppressing inflammation and restoring the cartilage matrix.
J. Mater. Chem. B, 2024,12, 4148-4161
https://doi.org/10.1039/D4TB00294F
Defect-rich sonosensitizers based on CeO2 with Schottky heterojunctions for boosting sonodynamic/chemodynamic synergistic therapy
A defect-rich hollow Schottky heterojunction sonosensitizer, constructed by defect engineering and noble metal enrichment, exhibits an amplified treatment effect for sonodynamic therapy due to the inhibition effect of electron–hole pair recombination.
J. Mater. Chem. B, 2024,12, 4162-4171
https://doi.org/10.1039/D4TB00084F
Engineering lauric acid-based nanodrug delivery systems for restoring chemosensitivity and improving biocompatibility of 5-FU and OxPt against Fn-associated colorectal tumor
The tailored nanomedicine 5-FU-LA@PPL could selectively combat Fn, inhibit autophagy in CRC cells, restore chemosensitivity of 5-FU as well as OxPt, and consequently enhance the combination chemotherapy effects for Fn-associated drug-resistant CRC.
J. Mater. Chem. B, 2024,12, 3947-3958
https://doi.org/10.1039/D4TB00103F
Efficient in vitro and in vivo transfection of self-amplifying mRNA with linear poly(propylenimine) and poly(ethylenimine-propylenimine) random copolymers as non-viral carriers
SaRNA was formulated with six different polymer carriers to generate saRNA-polyplexes. After screening for transfection efficiency, compared to a lipid-based standard, the best performing ones were characterized in detail and administered to mice.
J. Mater. Chem. B, 2024,12, 3927-3946
https://doi.org/10.1039/D3TB03003B
Rational design of type-I photosensitizer molecules for mitochondrion-targeted photodynamic therapy
Aryl functioned S-rhodamines were presented as mitochondrion-targeted photosensitizers with different photodynamic therapy activities.
J. Mater. Chem. B, 2024,12, 3686-3693
https://doi.org/10.1039/D4TB00099D
A peptide selectively recognizes Gram-negative bacteria and forms a bacterial extracellular trap (BET) through interfacial self-assembly
Nanoparticles identifying bacteria and forming a bacterial extracellular trap (BET). LPS induced in situ transformation and self-assembly of BET nanoparticles were shown to trap Gram-negative bacteria.
J. Mater. Chem. B, 2024,12, 3676-3685
https://doi.org/10.1039/D3TB02559D
Double crosslinking decellularized bovine pericardium of dialdehyde chondroitin sulfate and zwitterionic copolymer for bioprosthetic heart valves with enhanced antithrombogenic, anti-inflammatory and anti-calcification properties
Schematic diagram of the preparation process of P(APM/MPC)-OCS-BP and the function model of P(APM/MPC)-OCS-BP with anti-coagulation, anti-calcification, and anti-inflammatory properties and a high capacity to promote endothelial proliferation.
J. Mater. Chem. B, 2024,12, 3417-3435
https://doi.org/10.1039/D4TB00074A
Enzyme-triggered on-demand release of a H2O2-self-supplying CuO2@Fe3O4 nanoagent for enhanced chemodyamic antimicrobial therapy and wound healing
Schematic diagram of the preparation of the enzyme-responsive nanoplatform HA-CP@Fe3O4 and its application in the study of antibacterial infection in vivo.
J. Mater. Chem. B, 2024,12, 3404-3416
https://doi.org/10.1039/D3TB02762G
Radiation responsive PROTAC nanoparticles for tumor-specific proteolysis enhanced radiotherapy
An X-ray responsive RCNprotac with enhanced tumor accumulation for BRD4 proteolysis and enhanced radiosensitization is reported.
J. Mater. Chem. B, 2024,12, 3240-3248
https://doi.org/10.1039/D3TB03046F
H2O2-triggered controllable carbon monoxide delivery for photothermally augmented gas therapy
Nanotheranostics (IN-DPPCO NPs) based on a conjugated polymer IN-DPP and a carbon monoxide (CO) carrier polymer mPEG(CO) are reported for H2O2-triggered controllable carbon monoxide delivery for photothermal augmented gas therapy.
J. Mater. Chem. B, 2024,12, 2737-2745
https://doi.org/10.1039/D3TB02399K
A dual-targeted Gd-based contrast agent for magnetic resonance imaging in tumor diagnosis
A dual-targeted contrast agent, RGD-(DOTA-Gd)-TPP (RDP), was synthesized, in which RGD is used to target the αvβ3 integrin receptor overexpressed in tumor cells and TPP is used to bind to a mitochondrion further.
J. Mater. Chem. B, 2024,12, 2486-2493
https://doi.org/10.1039/D3TB02917D
Design of donor–acceptor conjugated polymers based on diketopyrrolopyrrole for NIR-II multifunctional imaging
Here, we designed and synthesized two donor–acceptor (D–A) conjugated polymers with DPP as the receptor. The polymer nanoparticles have broad application prospects in biological imaging and photothermal therapy.
J. Mater. Chem. B, 2024,12, 2294-2303
https://doi.org/10.1039/D3TB02864J
Engineering organelle-specific activatable molecules for ultra-fast and reliable in situ mapping of subcellular nitric oxide
A series of subcellular targeted probes with hypersensitivity (reaction time <60 s, detection limit at the nmol level) to nitric oxide (NO) were developed to map NO fluctuations at the subcellular level.
J. Mater. Chem. B, 2024,12, 2304-2312
https://doi.org/10.1039/D3TB02920D
An injectable photocuring silk fibroin-based hydrogel for constructing an antioxidant microenvironment for skin repair
An injectable photocurable hydrogel based on methacrylated dopamine and silk fibroin constructs an antioxidant protein microenvironment, which prevents oxidative stress in vitro, and promotes collagen disposition and angiogenesis in vivo.
J. Mater. Chem. B, 2024,12, 2282-2293
https://doi.org/10.1039/D3TB02214E
A two-in-one probe: imaging lipid droplets and endoplasmic reticulum in tandem
The endoplasmic reticulum (ER) and lipid droplets (LDs) intricately interact in cellular processes, with the ER serving as a hub for lipid synthesis and LDs acting as storage organelles for lipids.
J. Mater. Chem. B, 2024,12, 2028-2041
https://doi.org/10.1039/D4TB00026A
Mg-based implants with a sandwiched composite coating simultaneously facilitate antibacterial and osteogenic properties
Mg-based implants with a sandwiched coating simultaneously facilitate antibacterial and osteogenic properties due to the synergistic biological effects of TCS and Mg2+.
J. Mater. Chem. B, 2024,12, 2015-2027
https://doi.org/10.1039/D3TB02744A
Effective design of PEGylated polyion complex (PIC) nanoparticles for enhancing PIC internalisation in cells utilising block copolymer combinations with mismatched ionic chain lengths
Design factors of PEGylated polyion complex (PIC) nanoparticles, particularly PIC vesicles, were examined regarding polyion chain matching, domain crosslinking, and chemical modification of charged units, to modulate mammalian cell-PIC interaction.
J. Mater. Chem. B, 2024,12, 1826-1836
https://doi.org/10.1039/D3TB02049E
Schottky heterojunction CeO2@MXene nanosheets with synergistic type I and type II PDT for anti-osteosarcoma
Endogenous O2 can be continuously generated by the catalysis of Ce in the lattice of CeO2 to enhance 1O2 production via a type II PDT (energy transfer), and many other ROS (such as O2− and ·OH) can be produced via a type I PDT (electron transfer).
J. Mater. Chem. B, 2024,12, 1816-1825
https://doi.org/10.1039/D3TB02835F
Effect of zwitterionic sulfobetaine incorporation on blood behaviours, phagocytosis, and in vivo biodistribution of pH-responsive micelles with positive charges
A series of pH-responsive and sulfobetaine-incorporated micelles with positive charges is prepared, in which the effects of the sulfobetaine incorporation displayed different profiles in the blood behaviours, phagocytosis, and in vivo biodistribution.
J. Mater. Chem. B, 2024,12, 1652-1666
https://doi.org/10.1039/D3TB02477F
Precise design of dual active-site catalysts for synergistic catalytic therapy of tumors
A schematic of the fabrication of FePt-DAC/NC@HA and synergistic chemodynamic therapy and photothermal therapy for tumor catalytic therapy.
J. Mater. Chem. B, 2024,12, 1512-1522
https://doi.org/10.1039/D3TB02145A
A light-sensitive protein-based wearable pH biometer
A bR-based wearable pH biometer is fabricated to monitor infected wound. Under illumination, bR generate a positive photovoltage (Vp) and negative photovoltage (Vn), and the ratio (Vn/Vp) present a linear relationship in the pH range of 4.0–10.0.
J. Mater. Chem. B, 2024,12, 1208-1216
https://doi.org/10.1039/D3TB02466K
A multimodal therapy for infected diabetic wounds based on glucose-responsive nanocomposite-integrated microneedles
Antibacterial nanocomposite-integrated microneedles were designed for infected diabetic wound therapy. The nanocomposite could be destroyed by high glucose and exerted a powerful and synergistic antibacterial effect against bacterial infections.
J. Mater. Chem. B, 2024,12, 1007-1021
https://doi.org/10.1039/D3TB02609D
Synthetic macromolecular peptide-mimetics with amino acid substructure residues as protein stabilising excipients
The clinical use of protein and peptide biotherapeutics requires fabrication of stable products.
J. Mater. Chem. B, 2024,12, 1022-1030
https://doi.org/10.1039/D3TB02102E
About this collection
This on-going web collection features all the articles published in Journal of Materials Chemistry B in 2024 marked as HOT (selected by our Editors as especially significant based on reviewers’ recommendations and their own appraisal). Congratulations to all the authors whose articles are featured!