RSC Advances  

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Medical diagnostics articles published in the last 6 months

78 items - Showing page 1 of 4
Open Access Paper

Carboxyl-functionalized two-dimensional MXene–Au nanocomposites were prepared as SERS substrates for the detection of melamine in dairy products

In the present study, we address the limitations of conventional surface-enhanced Raman scattering (SERS) techniques for sensitive and stable detection of melamine in food products, especially dairy.

Graphical abstract: Carboxyl-functionalized two-dimensional MXene–Au nanocomposites were prepared as SERS substrates for the detection of melamine in dairy products
Open Access Paper

Detection of intracellular microRNA-21 for cancer diagnosis by a nanosystem containing a ZnO@polydopamine and DNAzyme probe

The novel nanosystem composed of ZnO@polydopamine nanomaterial and deoxyribozyme probe can be applied for ratiometric fluorescence assay for microRNA-21, which is helpful for cancer diagnosis and prognosis.

Graphical abstract: Detection of intracellular microRNA-21 for cancer diagnosis by a nanosystem containing a ZnO@polydopamine and DNAzyme probe
Open Access Paper

Automatic microdispenser-integrated multiplex enzyme-linked immunosorbent assay device with autonomously driven centrifugal microfluidic system

A design theory for an autonomously driven dispenser was established. The multiplexed ELISA device was integrated with the dispenser and CLOCK circuits, and successfully prepared a calibration curve of mouse IgG by rotating at a constant speed.

Graphical abstract: Automatic microdispenser-integrated multiplex enzyme-linked immunosorbent assay device with autonomously driven centrifugal microfluidic system
Open Access Paper

Selection, characterization, and biosensing applications of DNA aptamers targeting cyanotoxin BMAA

Scientists have established a connection between environmental exposure to toxins like β-N-methylamino-L-alanine (BMAA) and a heightened risk of neurodegenerative disorders.

Graphical abstract: Selection, characterization, and biosensing applications of DNA aptamers targeting cyanotoxin BMAA
Open Access Paper

Rapid and quantitative detection of DNA hybridization using a simplified Fabry–Perot interferometric biosensor

The simple-structured Fabry–Perot interferometric biosensor is capable of rapid and quantitative detection of DNA hybridization.

Graphical abstract: Rapid and quantitative detection of DNA hybridization using a simplified Fabry–Perot interferometric biosensor
Open Access Paper

A multi-channel microfluidic platform based on human flavin-containing monooxygenase 3 for personalised medicine

A microfluidic platform with immobilized human flavin-containing monooxygenase for high-throughput screening of drugs with relevance to personalised medicine.

Graphical abstract: A multi-channel microfluidic platform based on human flavin-containing monooxygenase 3 for personalised medicine
Open Access Paper

Quantitative analysis of the illegal addition of Atenolol in Panax notoginseng based on NIR–MIR spectral data fusion and calibration transfer

To address the issue of the common illegal addition of Atenolol in Panax notoginseng, we propose an approach that realizes multivariate calibration transfer between different particle sizes based on spectral data fusion.

Graphical abstract: Quantitative analysis of the illegal addition of Atenolol in Panax notoginseng based on NIR–MIR spectral data fusion and calibration transfer
Open Access Paper

Label-free detection of Aβ-42: a liquid crystal droplet approach for Alzheimer's disease diagnosis

This study introduces a biosensor based on liquid crystals (LC) designed to detect the Aβ-42 biomarker, commonly associated with Alzheimer's disease.

Graphical abstract: Label-free detection of Aβ-42: a liquid crystal droplet approach for Alzheimer's disease diagnosis
Open Access Paper

Detection of SARS-CoV-2 N protein using AgNPs-modified aligned silicon nanowires BioSERS chip

A sensitive and selective bioSERS chip was developed for the detection of nucleocapsid protein from SARS-CoV-2 virus, applied to sense the N protein in human blood serum.

Graphical abstract: Detection of SARS-CoV-2 N protein using AgNPs-modified aligned silicon nanowires BioSERS chip
Open Access Review Article

Skin emitted volatiles analysis for noninvasive diagnosis: the current advances in sample preparation techniques for biomedical application

Analytical technique for monitoring skin-emitted metabolites to diagnose diseases.

Graphical abstract: Skin emitted volatiles analysis for noninvasive diagnosis: the current advances in sample preparation techniques for biomedical application
From the themed collection: 2024 Reviews in RSC Advances
Open Access Paper

Detection and photothermal inactivation of Gram-positive and Gram-negative bloodstream bacteria using photonic crystal biosensor and plasmonic core–shell

This study introduces a tailored theoretical framework for a one-dimensional photonic crystal biosensor composed of (ZrO2/GaN)N/defect layer/(ZrO2/GaN)N, designed to detect Gram-positive and Gram-negative bloodstream bacteria employing the transfer matrix method.

Graphical abstract: Detection and photothermal inactivation of Gram-positive and Gram-negative bloodstream bacteria using photonic crystal biosensor and plasmonic core–shell
Open Access Review Article

Greening the pathways: a comprehensive review of sustainable synthesis strategies for silica nanoparticles and their diverse applications

The graphical abstract describes several synthetic routes of SiNPs and wide range of applications of this nanoparticle.

Graphical abstract: Greening the pathways: a comprehensive review of sustainable synthesis strategies for silica nanoparticles and their diverse applications
From the themed collection: 2024 Reviews in RSC Advances
Open Access Paper

A novel fluorescence probe for simultaneous detection of mitochondrial viscosity in hepatic ischemia reperfusion injury models

A versatile probe with mitochondria targeting, PN, for detection of viscosity alteration in HIRI mouse model was fabricated. PN had high sensitivity and selectivity, and with a large Stokes shift (∼190 nm) for viscosity. PN is expected to be used for early diagnosis and treatment assessment of HIRI disease, and also provides diagnostic basis for other related diseases.

Graphical abstract: A novel fluorescence probe for simultaneous detection of mitochondrial viscosity in hepatic ischemia reperfusion injury models
Open Access Review Article

Recent advances in photothermal nanomaterials-mediated detection of circulating tumor cells

This review summarizes the application of various photothermal materials in the detection of circulating tumor cells (CTCs), and describes the significance of CTCs detection for early tumor diagnosis and tumor prognosis.

Graphical abstract: Recent advances in photothermal nanomaterials-mediated detection of circulating tumor cells
From the themed collection: 2024 Reviews in RSC Advances
Open Access Paper

LC-MS/DIA-based strategy for comprehensive flavonoid profiling: an Ocotea spp. applicability case

A user-friendly LC-MS data-independent acquisition-based strategy using open software for access to the flavonoid content of complex mixtures.

Graphical abstract: LC-MS/DIA-based strategy for comprehensive flavonoid profiling: an Ocotea spp. applicability case
Open Access Paper

A new green fluorimetric micelle complexation approach for reduction of the consumed solvent and quantification of avapritinib in biological fluids

A novel green fluorimetric approach for quantifying avapritinib in biological fluids (pharmacokinetic study).

Graphical abstract: A new green fluorimetric micelle complexation approach for reduction of the consumed solvent and quantification of avapritinib in biological fluids
Open Access Review Article

Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration

Vitamins are crucial micronutrients found in limited quantities in food, living organisms, and soil.

Graphical abstract: Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration
From the themed collection: 2024 Reviews in RSC Advances
Open Access Paper

In situ imaging of mRNA transcripts based on split-aptamer and split protein in living cells

Messenger RNA (mRNA) is an essential component of cell development and growth.

Graphical abstract: In situ imaging of mRNA transcripts based on split-aptamer and split protein in living cells
Open Access Review Article

Recent advances in the fluorimetric and colorimetric detection of cobalt ions

Cobalt is an essential metal to maintain several functions in the human body and is present in functional materials for numerous applications.

Graphical abstract: Recent advances in the fluorimetric and colorimetric detection of cobalt ions
From the themed collection: 2024 Reviews in RSC Advances
Open Access Review Article

Recent advancements in the specific determination of carcinoembryonic antigens using MOF-based immunosensors

Carcinoembryonic antigens (CEAs) are prominent cancer biomarkers that enable the early detection of numerous cancers.

Graphical abstract: Recent advancements in the specific determination of carcinoembryonic antigens using MOF-based immunosensors
From the themed collection: 2024 Reviews in RSC Advances
Open Access Paper

Switch-on near infrared emission in albumin behind dark fabric: toward application in forensic latent bloodstain detection

Near infrared switch-on emission of SO3C7 in albumin allows imaging behind dark fabric which can inhibit latent blood stain detection.

Graphical abstract: Switch-on near infrared emission in albumin behind dark fabric: toward application in forensic latent bloodstain detection
Open Access Paper

Ultrasensitive colorimetric detection of creatinine via its dual binding affinity for silver nanoparticles and silver ions

Creatinine detection via dual binding affinity for silver nanoparticles and silver ions.

Graphical abstract: Ultrasensitive colorimetric detection of creatinine via its dual binding affinity for silver nanoparticles and silver ions
Open Access Review Article

Real-time fluorescent monitoring of phase I xenobiotic-metabolizing enzymes

Applications of chemosensors of phase I metabolizing enzymes.

Graphical abstract: Real-time fluorescent monitoring of phase I xenobiotic-metabolizing enzymes
From the themed collection: 2024 Reviews in RSC Advances
Open Access Paper

An innovative transportable immune device for the recognition of α-synuclein using KCC-1-nPr-CS2 modified silver nano-ink: integration of pen-on-paper technology with biosensing toward early-stage diagnosis of Parkinson's disease

Parkinson's disease (PD), the second most frequent neurodegenerative illness, is a neurological ailment that produces unintentional or uncontrolled body movements, which should be diagnosed in its early stages to hinder the progression.

Graphical abstract: An innovative transportable immune device for the recognition of α-synuclein using KCC-1-nPr-CS2 modified silver nano-ink: integration of pen-on-paper technology with biosensing toward early-stage diagnosis of Parkinson's disease
Open Access Paper

A prototype of ultrasensitive time-resolved fluoroimmunoassay for the quantitation of lead in plasma using a fluorescence-enhanced europium chelate label for the detection system

This study describes the development and validation of a prototype time-resolved fluoroimmunoassay (TRFIA) for the quantification of lead in plasma. The assay is valuable for controlling the exposure of humans to potential lead toxicities.

Graphical abstract: A prototype of ultrasensitive time-resolved fluoroimmunoassay for the quantitation of lead in plasma using a fluorescence-enhanced europium chelate label for the detection system
78 items - Showing page 1 of 4

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