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Themed collection JMC B Editor’s choice web collection: ‘‘seeing the unseen updated: advances in bioimaging’’

21 items
Editorial

Journal of Materials Chemistry B Editor's choice web collection: “Seeing the unseen updated: advances in bioimaging”

Xiaogang Qu introduces a Journal of Materials Chemistry B Editor's choice web collection on advances in bioimaging (http://rsc.li/BioimagingAdvances).

Graphical abstract: Journal of Materials Chemistry B Editor's choice web collection: “Seeing the unseen updated: advances in bioimaging”
Review Article

Optical nanoprobes for biomedical applications: shining a light on upconverting and near-infrared emitting nanoparticles for imaging, thermal sensing, and photodynamic therapy

Shining a light on spectrally converting lanthanide (Ln3+)-doped nanoparticles: progress, trends, and challenges in Ln3+-nanoprobes for near-infrared bioimaging, nanothermometry, and photodynamic therapy.

Graphical abstract: Optical nanoprobes for biomedical applications: shining a light on upconverting and near-infrared emitting nanoparticles for imaging, thermal sensing, and photodynamic therapy
From the themed collection: Recent Review Articles
Review Article

Heteroatom-doped carbon dots: synthesis, characterization, properties, photoluminescence mechanism and biological applications

This review summarized the recent progress in the synthesis, characterization, properties, photoluminescence mechanism and biological applications of carbon dots.

Graphical abstract: Heteroatom-doped carbon dots: synthesis, characterization, properties, photoluminescence mechanism and biological applications
Review Article

Carbon dots: surface engineering and applications

Surface engineering of carbon dots and their applications in targeting sensing, accurate drug delivery and high resolution bioimaging are highlighted.

Graphical abstract: Carbon dots: surface engineering and applications
Paper

A novel near-infrared fluorescent probe with a large Stokes shift for biothiol detection and application in in vitro and in vivo fluorescence imaging

A novel near-infrared fluorescent probe with a large Stokes shift was developed for biothiol detection and application in in vitro and in vivo fluorescence imaging.

Graphical abstract: A novel near-infrared fluorescent probe with a large Stokes shift for biothiol detection and application in in vitro and in vivo fluorescence imaging
Paper

A NIR fluorescent chemodosimeter for imaging endogenous hydrogen polysulfides via the CSE enzymatic pathway

Sodium polysulfides (Na2Sn, n > 1) as important raw materials in the chemical industry can afford hydrogen polysulfides (H2Sn, n > 1) under physiological conditions.

Graphical abstract: A NIR fluorescent chemodosimeter for imaging endogenous hydrogen polysulfides via the CSE enzymatic pathway
Paper

Development of a unique family of two-photon full-color-tunable fluorescent materials for imaging in live subcellular organelles, cells, and tissues

We outline the rational design, synthesis, optical property studies, and biological imaging studies of a unique family of two-photon full-color-tunable functional fluorescent materials.

Graphical abstract: Development of a unique family of two-photon full-color-tunable fluorescent materials for imaging in live subcellular organelles, cells, and tissues
Paper

An aza-BODIPY photosensitizer for photoacoustic and photothermal imaging guided dual modal cancer phototherapy

A novel NIR absorbing aza-BODIPY photosensitizer with high 1O2 quantum yield and excellent photothermal conversion efficiency was designed for synergistic phototherapy.

Graphical abstract: An aza-BODIPY photosensitizer for photoacoustic and photothermal imaging guided dual modal cancer phototherapy
Paper

Targetable and fixable rotor for quantifying mitochondrial viscosity of living cells by fluorescence lifetime imaging

A fixable probe, named Vis-A, to quantify mitochondrial viscosity of living cells by fluorescence lifetime imaging.

Graphical abstract: Targetable and fixable rotor for quantifying mitochondrial viscosity of living cells by fluorescence lifetime imaging
Paper

A mitochondria-targeted ratiometric fluorescent probe for hypochlorite and its applications in bioimaging

A novel ratiometric probe (RCP) for OCl was developed based on the fluorescence resonance energy transfer (FRET) platform.

Graphical abstract: A mitochondria-targeted ratiometric fluorescent probe for hypochlorite and its applications in bioimaging
Paper

One-pot synthesis of gadolinium-doped carbon quantum dots for high-performance multimodal bioimaging

A high-performance fluorescence (FL)/magnetic resonance (MR) imaging probe is synthesized by doping Gd3+ into carbon quantum dots via a one-pot pyrolysis process, and its dual-modality applications are demonstrated by the use of HeLa cells and mice as models.

Graphical abstract: One-pot synthesis of gadolinium-doped carbon quantum dots for high-performance multimodal bioimaging
Paper

Highly efficient NIR to NIR upconversion of ZnMoO4:Tm3+,Yb3+ phosphors and their application in biological imaging of deep tumors

In vivo imaging of deep tumor in nude-mice was successfully demonstrated using highly efficient ZnMoO4:Tm3+,Yb3+,K+ nano-phosphors and an 810 nm NIR laser.

Graphical abstract: Highly efficient NIR to NIR upconversion of ZnMoO4:Tm3+,Yb3+ phosphors and their application in biological imaging of deep tumors
Paper

Preparation of fluorescent Au–SiO2 core–shell nanoparticles and nanorods with tunable silica shell thickness and surface modification for immunotargeting

Scalable methods for preparing and modifying Au–SiO2 core–shell nanoparticles provide a platform for engineering size-dependent multifunctional properties for in vivo biomedical applications.

Graphical abstract: Preparation of fluorescent Au–SiO2 core–shell nanoparticles and nanorods with tunable silica shell thickness and surface modification for immunotargeting
Paper

Fabrication of hybridized nanoparticles with aggregation-induced emission characteristics and application for cell imaging

More TPE-CS/HA nanoparticles are endocytosed by culture for a long time, resulting in a much stronger fluorescence emission.

Graphical abstract: Fabrication of hybridized nanoparticles with aggregation-induced emission characteristics and application for cell imaging
Paper

Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells

A novel pyrano[3,2-c]julolidin-2-one based fluorescent molecular rotor PYJO4 has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg2+ in live cells.

Graphical abstract: Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells
Open Access Paper

Cellular internalisation, bioimaging and dark and photodynamic cytotoxicity of silica nanoparticles doped by {Mo6I8}4+ metal clusters

{Mo6I8}@SiO2 nanoparticles for biomedical applications.

Graphical abstract: Cellular internalisation, bioimaging and dark and photodynamic cytotoxicity of silica nanoparticles doped by {Mo6I8}4+ metal clusters
Paper

A lysosome-targeted and ratiometric fluorescent probe for imaging exogenous and endogenous hypochlorous acid in living cells

We have developed the first small-molecule based, lysosomal-targeted ratiometric fluorescent HClO probe (Lyso-HA). Fluorescence imaging shows that it is suitable for ratiometric visualization of exogenous and endogenous HClO at lysosomes in living cells.

Graphical abstract: A lysosome-targeted and ratiometric fluorescent probe for imaging exogenous and endogenous hypochlorous acid in living cells
Paper

Facile fabrication of amphiphilic AIE active glucan via formation of dynamic bonds: self assembly, stimuli responsiveness and biological imaging

A one-pot strategy has been developed for the preparation of stimuli responsive AIE active glucan through formation of a dynamic Schiff base and a phenyl borate.

Graphical abstract: Facile fabrication of amphiphilic AIE active glucan via formation of dynamic bonds: self assembly, stimuli responsiveness and biological imaging
Paper

A hydrothermal reaction of an aqueous solution of BSA yields highly fluorescent N doped C-dots used for imaging of live mammalian cells

In the current study, we present a new and facile synthesis of N doped C-dots (N@C-dots) by hydrothermally reacting an aqueous solution of Bovine Serum Albumin (BSA) for imaging of live mammalian cells.

Graphical abstract: A hydrothermal reaction of an aqueous solution of BSA yields highly fluorescent N doped C-dots used for imaging of live mammalian cells
Paper

Rationally designed two-photon absorption compounds based on benzoxazole derivatives: structure–property relationships and bio-imaging applications

Five rationally designed benzoxazole-based two photon absorption compounds were reported and their structure–property relationships were summarized clearly.

Graphical abstract: Rationally designed two-photon absorption compounds based on benzoxazole derivatives: structure–property relationships and bio-imaging applications
Paper

A photostable AIEgen for nucleolus and mitochondria imaging with organelle-specific emission

A dual-color organelle-specific probe with the AIE feature for mitochondria and nucleolus is developed. Due to the different interactions with mitochondrial membrane and nucleic acids, distinct emission colors from mitochondria and nucleolus are observed under a fluorescence microscope.

Graphical abstract: A photostable AIEgen for nucleolus and mitochondria imaging with organelle-specific emission
21 items

About this collection

This first in a two-part series of JMC B Editor’s choice web collections focusses on the recent advances in bioimaging.

Journal of Material Chemistry B’s Associate Editor Xiaogang Qu (Chinese Academy of Sciences, CIAC, China) has gathered together the journal’s most outstanding recent papers on bioimaging with crucial real world applications.

Browse this collection to view reviews and original research demonstrating the unparalleled potential in personalized treatment, early detection, point-of-care, and accurate diagnoses and the many interesting results published in this exciting field. This Editor’s choice web collection entitled ‘‘seeing the unseen updated: advances in bioimaging’’ highlights Journal of Materials Chemistry B’s most outstanding papers in functional materials-based bioimaging.

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