Themed collection Journal of Materials Chemistry B Recent Review Articles

Advances in bioactive regenerative polymeric scaffolds continue to be made with new materials and methods of characterization.

Micro/nanomotor swarms propelled by diverse mechanisms.

Intestinal retentive devices (IRDs) are devices designed to anchor within the lumen of the intestines for long-term residence in the gastrointestinal tract.

Hydrogel loaded GQDs can be used for targeted bioimaging in specific diseases, including cancer, due to their small size and biocompatibility. GQDs have potential for application in cancer therapy and ability to absorb radiation to make them suitable for photothermal and photodynamic therapies.

Magnetoelectric composites are currently used in a number of applications and promote bone regeneration via multiple mechanisms.

The area of drug delivery systems has witnessed significant advancements in recent years, with a particular focus on improving efficacy, stability, and patient compliance.

Recent advancements pertaining to the application of GQD-based nanosystems in photothermal and photodynamic cancer therapies are discussed, highlighting crucial challenges, advantages, and future perspectives.

In situ self-assembly of peptides in living cells regulated by biocompatible stimuli allows for precise creation of well-defined nanostructures and thus offering a versatile strategy for formulation of biomedical agents at pathological lesions.

Research progress of the UCNPs–MoS₂ nanoplatform in biological applications such as biosensing, phototherapy, bioimaging, and targeted drug delivery.

Reprogramming anti-inflammatory macrophages into pro-inflammatory type becomes an efficient antitumor therapeutic approach. With the development of nanotechnology, the strategy of using nanomaterials is an effective option for TAM repolarization.

This review focuses on the versatile applications of near-infrared (NIR)-responsive smart carriers in biomedical applications, particularly drug delivery and photothermal chemotherapy.

A comprehensive review of the current landscape and advancements in vaccine adjuvants, providing critical insights into research, development, regulatory licensing, and potential future opportunities for enhancing vaccine efficacy and safety.

Manganese-based nanoparticles exhibit the multiple roles of immune adjuvants, photosensitizers and photothermal agents in photo-immunotherapy, enhancing anti-tumor immunity through multiple ways.

We explore how DNA assembly, including 2D techniques, as well as 3D structures, enhances DNA methyltransferases detection. We highlight the benefits of these DNA nanostructure-based biosensing technologies for clinical use and examine the challenges of standardizing these methods.

An illustrative depiction highlighting the targeted drug delivery mechanism by bio-functionalized camouflaged MOF nanocarriers that enhances precision by targeting diseased cells and minimizing side effects.

Recent advancements pertaining to the application of 3D, 4D, 5D, and 6D bioprinting in cancer research are discussed, focusing on important challenges and future perspectives.

This paper provides a comprehensive review of the structure, composition, and applications of LNPs in the treatment of hepatic disorders and offers insights into prospects and challenges in the future development of LNPs.

This review highlights the ring-opening polymerization strategies of LA molecules and recent biomedical applications of PLA while discussing the challenges they face and future perspectives.

Nanomedicine-induced pyroptosis for efficient antitumor immunotherapy has been increasingly prominent at the current stage. In this review, we provide a comprehensive summary and deep discussion on the very-recent progresses achieved in this field.

This review summarizes the application of native and engineered EVs to treat various liver diseases, which helps understand the current scenario and future research direction.

This review article explores the innovative field of eco-friendly cyclodextrin-based coordination polymers and metal–organic frameworks (MOFs) for transdermal drug delivery in the case of skin cancer therapy.

NIR-driven UCNPs with photocatalysts can absorb UV/vis light via water splitting. Water splitting enables in situ H₂, O₂, and OH˙ generation under a light source. The nanocomposites can enhance therapeutic approaches for cancer treatment.

The adaptability of MOFs allows precise detection and quantification of amyloid proteins. This study delves into how MOFs contribute to detecting amyloid diseases, sorting their uses according to different sensing methods.

This review for the first time summarizes the structure–function relationship between MOFs and toxin adsorption, as well as the biocompatibility and practicality for HD, HP, and ECMO. It is anticipated that this review will expand the interest of researchers for more impact in this area.

Illustration of ultrasound-induced enhancement of cancer immunotherapy.

Photothermal therapy (PTT) is a minimally invasive procedure that uses nanoparticles to produce heat from light to kill cancer cells. This review highlights the mechanism of PTT, and the results obtained for the improved therapeutic effect of PTT using the inorganic nanoparticles platform.

IBionic vector constructs have shown therapeutic efficacy in inflammatory bowel disease due to their highly biocompatible “self” nature and specificity in targeting tissues and organs.

Nanocarriers hold great potential for engineering immune cells based on their performance (efficiency, safety and specificity). This review focuses on different stages of the transfection process and some important challenges.

Microneedles that can be inserted and attached to multiple organ sites are considered an innovative platform for delivering anti-tumor drugs, which can be used in various tumor treatment protocols.

Six commonly used synthesis techniques for calcium phosphates are solid-state, mechano-chemical, wet-chemical precipitation, hydrolysis, sol–gel, and hydrothermal methods.

Many human health problems and property losses caused by pathogenic contamination cannot be underestimated.

This review summarizes fabrication strategies and manifold applications of electrospun organic/inorganic hybrid nanofibers in promoting the wound healing process.

Advanced nanotechnology developed for PD-L1 detection and PD-L1/PD-1 immune checkpoint-relevant combined cancer therapies is reviewed.

This review summarizes the recent advances of nanoplatform-based strategies to efficiently amplify the tumoricidal capability of PDT.

This review highlights the design and engineering of ZnO based 0–3D nano-architectures, thin films and coatings with tunable characteristics for multifunctional biomedical applications.

This review focuses on fluorescence mechanisms for viscosity responsiveness, highlighting some important probes like coumarin, BODIPY, and xanthene as well as the application of these viscosity-sensitive probes for successful diabetes detection.

The standard treatment for non-muscle invasive bladder cancer (NMIBC) is transurethral resection of bladder tumor (TURBT).

Various modification strategies have been used to improve the physicochemical and biological properties of PEEK as orthopedic implants.

HKUST-1 represents a promising biomaterial, functioning not only as a drug carrier but also releasing bioactive copper ions, thereby demonstrating exceptional antitumor, antibacterial, and wound healing properties.

Over the past two decades, metal–organic frameworks (MOFs) have garnered substantial scientific interest across diverse fields, spanning gas storage, catalysis, biotechnology, and more.

Combining phototherapies, particularly PDT and PTT, with immunotherapy synergistically stimulates immune responses, offering promising strategies for effective cancer treatment and prevention of recurrence.

Lignocellulosic-biomolecule conjugated systems represent potential eco-friendly materials applicable across various fields, including medicine, environmental sciences, food packaging, and agriculture.

Nanozymes demonstrate catalytic activities that can modulate ROS levels in leukemia cells, presenting a promising approach for treating leukemia.

Schematic illustration of roles and targets of immunoregulatory cells and hydrogel design strategies to promote wound healing.

Plant-derived exosomes (PDEs) show promising potential to be developed as a therapeutic agent against cancer, owing to their multiple advantages such as low toxicity, biocompatibility, availability, affordability, etc.

Peptide-based bioactive hydrogels exhibit high potential for nerve repair and regeneration applications via structural and functional regulations.

Effective immune response is an indispensable process for peripheral nerve regeneration and the tissue engineering strategies provide an approach for regulating immune cells that promote nerve repair.

Stereo-specific effects of chiral nanomaterials on protein-aggregated diseases.

The treatment of chronic refractory wounds poses significant challenges and threats to both human society and the economy.

Advantages of rare earth-doped nanoparticles in second near-infrared fluorescence imaging and commonly used rare earth ions.

Spinal diseases often result in compromised mobility and diminished quality of life due to the intricate anatomy surrounding the nervous system.

This review summarizes the design strategies and recent research progress of stimuli-responsive peptide hydrogels for biomedical applications.

Nanocarriers loaded with anticancer agents strategically intervene to block cell signaling pathways in glioblastoma.

Uncontrolled hemorrhage results in various complications and is currently the leading cause of death in the general population.

Cancer remains one of the deadliest diseases, and is characterised by the uncontrolled growth of modified human cells.

Dental caries caused mineral loss and degradation of organic matrix in dental hard tissues. In this review, we highlighted recent advances concerning electrospun nanofibers for caries lesions' treatment.

Pathological features of liver fibrosis, clinical treatment and application of therapeutic nanoagents for liver fibrosis.

Magnetic 2D nanocomposites exhibit advanced antitumor applications, including magnetically targeted hyperthermia, drug delivery, phototherapy, nanozyme therapy, immunotherapy and multimodal imaging.

This review highlights the latest progress of smart hydrogel dressings for bandaging, monitoring and therapy of diabetic wounds.

Butyrylcholinesterase (BChE) is a human serine hydrolase, which plays critical roles in various physiological and pathological states. Here, we summarized the optical probes that can selectively monitor the BChE activity in different biological models.

This review will provide guidelines for the “synergistic antimicrobial and antitumour” drug delivery strategy.

The size effect, optical, and electrical properties of recently developed nanomaterials for building sensors and their advantages and recent applications in biosensing are reviewed. Problems, challenges, and prospects are emphasized.

Recent advancements, important challenges, advantages, and future prospects of MXenes and their composites in E-skins are deliberated.

Two-dimensional nanomaterials (2D NMs) refer to nanomaterials that possess a planar topography with a thickness of one or several atomic layers.

ZIF-8 nanoparticles, with large surface area and pore capacity, can be functionalized for targeted cancer treatment. This enhances chemotherapeutic drug efficacy and potentially improves PD-1 inhibitors’ effectiveness.

In this study, we summarized the advantages and disadvantages of three types of reparative biomaterials for infectious maxillofacial bone defects at the present stage and provided insights into their future development directions.

This review highlights the recent advances of MOFs and their related hybrids in main implant intervention fields, while also discussing their confronting challenges and future perspectives.

Cerium vanadate nanoparticles (CeVO₄ NPs), which are members of the rare earth orthovanadate nanomaterial family, have generated considerable interest due to their diverse properties and prospective biomedical applications.