Themed collection Metal-Organic Frameworks: Celebrating the 2025 Nobel Prize in Chemistry

This review dissects structural engineering strategies for hierarchical MOFs/derivatives, evaluating their electrochemical energy storage performance as advanced electrodes, and critically assesses future design opportunities and challenges.

Thiazolothiazole-based MOFs offer a versatile platform for multifunctionality. This highlight reviews ligand design, synthesis methods, applications, challenges, and future trends.

This review explores the synthesis, drug loading, and surface modifications of metal–organic frameworks (MOFs), highlighting their role in improving cancer immunotherapy and paving the way for safer and more effective treatments.

This detailed review highlights the synergy between AIE and MOF chemistry, thereby exploring multifunctional AIE-MOF platforms for advanced sensing and imaging applications.

ZIF-8 MOFs and their hybrid materials: overview, synthesis methods and photocatalytic applications.

Review of physisorption (van der Waals, molecular sieving) and chemisorption (functional groups, metal sites) mechanisms enhancing CO₂ capture, highlighting recent advancements.

Clarifying the dose sensitivity of soft porous crystals (SPCs), particularly soft/flexible metal–organic framework (MOFs), is vital for optimizing precision-driven and large-scale applications across multiple advanced technologies.

In situ strategies to construct MOF-based MMMs are reviewed in the present study.

A comprehensive review of techniques and emerging trends in lanthanide-based MOFs for photocatalytic hydrogen evolution via water splitting.

Metal–organic frameworks (MOFs) are promising materials for hydrogen (H₂) storage due to their versatile structures, high surface areas and substantial pore volumes.

The design and synthesis of MOFs have evolved from traditional large-scale approaches to function-oriented modifications, and recently to AI predictions, which save time, reduce costs, and enhance the efficiency to achieving target functions.

Lithium extraction attracts great attention due to the rising demand for batteries, but faces challenges related to low natural abundance and environmental concerns. MOFs show promise in lithium extraction, benefitting from customizable structures.

Metal–organic frameworks (MOFs) have emerged as a transformative class of materials, offering unprecedented versatility in applications ranging from energy storage to environmental remediation and photocatalysis.

The panorama of the latest developments of the emerging porphyrin-based MOFs for photo(electro)catalytic CO₂ reduction is shown.

This review highlights the design and synthesis of water-stable MOFs, as well as their applications in carbon capture.

Metal–organic frameworks have advanced adsorption, photocatalysis and sensing of water contaminants.

Metal organic frameworks (MOFs) have captured immense attention in the last decade, owing to their better adsorption properties as compared to those of organic as well as inorganic materials, like enormous surface area, highly porous nature, tunable pore size, and high stability.

MOFs and other advanced emerging porous materials (i.e., COFs, POCs) have demonstrated tuneable structural and photoluminescent features, which can be helpful to monitor highly toxic SO₂ and H₂S pollutants using fluorescence spectroscopy techniques.

SWOT analysis of MOFs through the lens of safe and sustainable by design (SSbD) framework, highlighting their potential, challenges, and future directions (Prepared using Biorender Software).

Micro- and meso-porous lanthanide-based on metal–organic frameworks (Ln-MOFs) have been gaining significant attention for the last three decades as they offer diverse applications in a large number of areas.

This review introduces the recent advances in dual-emission MOF-based ratiometric fluorescence sensors for various targets such as pH, temperature, ions, biomarkers, etc., over the last 5 years.

A hard and soft acid and base theory guided “ship-in-a-bottle” strategy to incorporate bismuth nanoparticles inside a thiol-rich MOF unlocking dual catalytic activities.

Synthesis optimisation and a reproducibility study of the titanium-based MOF NTU-9 with a detailed (in situ) characterisation lead to the discovery of its flexibility upon external stimuli (e.g., vacuum) and the new distorted form NTU-9-d.

Molecular mechanisms governing alkali metal ion uptake from aqueous solution in MOF-808 are studied via free-energy calculations and enhanced sampling simulations, revealing the subtle interplay between hydration structure and confinement effects.

Selective crystallization of a novel thorium metal–organic framework (NU-2500) enables the efficient separation of Th(IV) from initial mixtures with rare earth(III) ions.

A series of isoreticular ultramicroporous fluorinated MOFs were synthesized. Both experimental and simulation studies showed that increasing the fluorine content leads to a marked increase in CO₂/N₂ selectivity owing to the CF⋯C(CO₂) interactions.

Spoiler alert: Claude and Gemini did better than GPT-4 in extracting information from chemistry literature.

A topologically diverse MOF dataset, NU-topoMOF-2025, was constructed and screened to identify topology-based design rules for materials with enhanced hydrogen storage performance.

Electron-correlation driven structural instability reveals mechanism of remarkable adsorption and seperation profiles observed experimentally.

Two differently entangled pillared MOFs have been evaluated for their host capacity towards pyridines and quinolines, showing markedly different inclusion propensity and stability.

A closed-loop robotic and computer vision system was developed to control and quantify MOF crystallization outcomes.

A Cu(I)-NHC motif was integrated into a 3D Zn-MOF utilizing an imidazolium ligand. The resulting Cu(I)-NHC@Zn-MOF exhibited high efficiency in catalyzing the carboxylation of terminal alkynes with carbon dioxide at atmospheric pressure.

Amine-functionalized Ce(III) MOF enables efficient CO₂-to-cyclic carbonate conversion via synergistic acid–base catalysis, showcasing high stability, reusability, and potential for CO₂ fixation.

Cu-BTC shows good CO₂/He, CH₄/He, and N₂/He separation performance, with enhanced performance at lower temperatures. The adsorption capacity and selectivity of Cu-BTC for helium-containing mixed gases are dominated by its open metal sites.

We demonstrate the one-pot conversion of CO₂ into amorphous formate-based metal–organic frameworks (MOFs) that form grain-boundary-free monoliths with permanent porosity through hot-pressing.

A novel folic acid-conjugated, iron-based metal framework MIL-101 (Fe) MOF loaded with 1,8-acridinediones (DO8) was developed for targeted photodynamic therapy (PDT).

MOFs formed from 8-connecting nodes and 4-connecting linkers can have the flu, scu and csq topologies. Here we show design criteria for making the rare sqc topology and how topology can be used to generate distinct post-synthetic metalation sites.

A stacked 2D Cu(I) coordination polymer displays electrical conductivity with DFT calculations revealing a band structure comprised of donor TCNQ^II− and acceptor 2,5-dimethylpyrazine p-orbitals.

A high radioluminescence sensitivity and low detection limit terbium-based metal–organic framework scintillator was applied for high-resolution flexible X-ray imaging.