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Themed collection New methods for isolation and structure determination of natural products

12 items
Cover

Front cover

Graphical abstract: Front cover
Cover

Inside front cover

Graphical abstract: Inside front cover
Editorial

New methods for isolation and structure determination of natural products

The Natural Product Reports themed issue on New Methods for Isolation and Structure Determination of Natural Products is introduced by the Guest Editors, Roger Linington, Julia Kubanek and Hendrik Luesch.

Graphical abstract: New methods for isolation and structure determination of natural products
Highlight

Imaging mass spectrometry for natural products discovery: a review of ionization methods

This mini review discusses advantages, limitations, and examples of different mass spectrometry ionization sources applicable to natural product discovery workflows.

Graphical abstract: Imaging mass spectrometry for natural products discovery: a review of ionization methods
Open Access Highlight

Innovative omics-based approaches for prioritisation and targeted isolation of natural products – new strategies for drug discovery

This review focuses on innovative omics approaches related to the prioritisation of natural extracts, to selection of efficient producing strains and to the targeted isolation of their bioactive constituents.

Graphical abstract: Innovative omics-based approaches for prioritisation and targeted isolation of natural products – new strategies for drug discovery
Review Article

Computational prediction of chiroptical properties in structure elucidation of natural products

A tutorial review aimed to introduce natural product chemists to the predictions of natural product configurations by ECD and OR calculations.

Graphical abstract: Computational prediction of chiroptical properties in structure elucidation of natural products
Review Article

Natural products targeting strategies involving molecular networking: different manners, one goal

This review focuses on the ever-expanding repertoire of molecular networking applications for targeting natural products.

Graphical abstract: Natural products targeting strategies involving molecular networking: different manners, one goal
Open Access Review Article

Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature

The chemistry of nature can be beautiful, inspiring, beneficial and poisonous, depending on perspective.

Graphical abstract: Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature
Review Article

Approaches for the isolation and identification of hydrophilic, light-sensitive, volatile and minor natural products

Water-soluble, volatile, minor and photosensitive natural products are yet poorly known, and this review discusses the literature reporting the isolation strategies for some of these metabolites.

Graphical abstract: Approaches for the isolation and identification of hydrophilic, light-sensitive, volatile and minor natural products
Open Access Review Article

Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2

This report documents the cellular, molecular, and analytical methods used to identify combination effects in complex natural product mixtures.

Graphical abstract: Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2
Review Article

Applications of OR/ECD/VCD to the structure elucidation of natural products

OR, ECD and VCD are powerful methods to determine the absolute configuration of natural products either applied independently or in combination.

Graphical abstract: Applications of OR/ECD/VCD to the structure elucidation of natural products
Review Article

The role of computer-assisted structure elucidation (CASE) programs in the structure elucidation of complex natural products

Computer-assisted structure elucidation can help to determine the structures of complex natural products while minimizing the risk of structure errors.

Graphical abstract: The role of computer-assisted structure elucidation (CASE) programs in the structure elucidation of complex natural products
12 items

About this collection

This themed issue is Guest Edited by Professor Julia Kubanek, Professor Roger Linington and Professor Hendrik Luesch  

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