Editorial “metallomics: emerging investigators”
Metallomics editorial board member Rachel Austin introduces our first group of Emerging Investigators in this themed issue dedicated to highlighting young scientists and their exciting research.
Arsenic metabolism and thioarsenicals
We discuss the current state of knowledge regarding the proposed mechanisms of arsenic biotransformation, and also look at cellular uptake, toxicity and clinical utilization of arsenicals.
Siderophore-based detection of Fe(III) and microbial pathogens
This minireview summarizes siderophore-based methods for the fluorescence detection of Fe(III) and capture of bacterial pathogens.
X-ray reduction correlates with soaking accessibility as judged from four non-crystallographically related diiron sites
X-ray reduction of diiron sites in a metalloprotein crystal correlates with their soaking accessibility, indicating that a diffusion component is involved in the reduction process.
metalloproteins through X-ray fluorescence mapping and mass spectrometry
Metals are critical and dynamic cellular components.
Genes for iron metabolism influence circadian rhythms in Drosophila melanogaster
Genes for iron metabolism have been implicated in the function of the biological clock in fly neurons.
triazole– pyridine derivatives as inhibitors of metal-induced amyloid-β aggregation
A series of four triazole–pyridine ligands were found to limit the metal-induced aggregation of the amyloid-β peptide relevant to Alzheimer's disease pathology.
Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation
A prochelator named BHAPI converts to the chelator HAPI upon reaction with H2O2 and protects cells under oxidative stress induced directly by H2O2 or indirectly by the cytotoxic herbicide paraquat.
About this collection
An issue dedicated to highlighting young scientists and their exciting research in the field of metal biology.