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Themed collection Metallomics 2018 Most Downloaded Articles

10 items
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Iron–sulfur cluster biosynthesis and trafficking – impact on human disease conditions

Iron–sulfur cluster biogenesis and trafficking enables the function of a number of cellular proteins. As such, mutations or perturbations in these pathways lead to disease states.

Graphical abstract: Iron–sulfur cluster biosynthesis and trafficking – impact on human disease conditions
From the themed collection: Recent Review Articles
Critical Review

Exploring the alternatives of biological nitrogen fixation

Most biological nitrogen fixation (BNF) results from the activity of the molybdenum nitrogenase (Mo-nitrogenase, Nif), an oxygen-sensitive metalloenzyme complex found in all known diazotrophs.

Graphical abstract: Exploring the alternatives of biological nitrogen fixation
From the themed collection: Recent Review Articles
Critical Review

Protein networks in the maturation of human iron–sulfur proteins

The maturation of human Fe–S proteins is a complex process involving protein–protein interaction networks distributed across different cellular compartments.

Graphical abstract: Protein networks in the maturation of human iron–sulfur proteins
From the themed collection: Recent Review Articles
Open Access Communication

Single-cell analysis by ICP-MS/MS as a fast tool for cellular bioavailability studies of arsenite

A fast and reliable single-cell ICP-MS/MS method is presented to determine the bioavailability of metal species as well as sulfur and phosphorus as internal control after re-suspension of cells in water.

Graphical abstract: Single-cell analysis by ICP-MS/MS as a fast tool for cellular bioavailability studies of arsenite
From the themed collection: Metallomics 2018 Most Downloaded Articles
Paper

Multimodal LA-ICP-MS and nanoSIMS imaging enables copper mapping within photoreceptor megamitochondria in a zebrafish model of Menkes disease

Coregistering quantitative high-resolution metal imaging with fluorescence imaging identifies copper accumulation in megamitochondria within intact neuroretinal slices.

Graphical abstract: Multimodal LA-ICP-MS and nanoSIMS imaging enables copper mapping within photoreceptor megamitochondria in a zebrafish model of Menkes disease
From the themed collection: Metallomics Recent HOT articles
Open Access Paper

The P-type ATPase inhibiting potential of polyoxotungstates

Polyoxometalates (POMs) are transition metal complexes that exhibit a broad diversity of structures and properties rendering them promising for biological purposes.

Graphical abstract: The P-type ATPase inhibiting potential of polyoxotungstates
From the themed collection: Metallomics 2018 Most Downloaded Articles
Paper

Synergistic gold–copper detoxification at the core of gold biomineralisation in Cupriavidus metallidurans

Cupriavidus metallidurans escapes synergistic Cu/Au toxicity by re-oxidation of Au(I) back to Au(III) using the periplasmic oxidase CopA.

Graphical abstract: Synergistic gold–copper detoxification at the core of gold biomineralisation in Cupriavidus metallidurans
From the themed collection: Metallomics 2018 Most Downloaded Articles
Open Access Paper

Interdependence of free zinc changes and protein complex assembly – insights into zinc signal regulation

Small and local changes in cellular free zinc concentration affect protein assembly.

Graphical abstract: Interdependence of free zinc changes and protein complex assembly – insights into zinc signal regulation
From the themed collection: Metallomics 2018 Most Downloaded Articles
Paper

Mobilization of iron from ferritin: new steps and details

Much evidence indicates that iron stored in ferritin is mobilized through protein degradation in lysosomes, but concerns about this process have lingered, and mechanistic details of its aspects are lacking.

Graphical abstract: Mobilization of iron from ferritin: new steps and details
From the themed collection: Metallomics 2018 Most Downloaded Articles
Open Access Paper

Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action

Transcriptomic, phenotypic and high throughput data reveal unique anticancer mechanisms shared by organometallic iridium and osmium complexes.

Graphical abstract: Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action
From the themed collection: Metallomics 2018 Most Downloaded Articles
10 items

About this collection

This themed collection features the top 10 most downloaded articles published in Metallomics in 2018. Congratulations to all of the authors whose articles have been featured.

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