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Themed collection Engineering Nanoparticles for Sensing and Biomedical Applications

9 items
Editorial

Engineering nanoparticles for sensing and biomedical applications: a themed collection

Guest editors Niveen M. Khashab, Jean-Olivier Durand and Jeffrey I. Zink introduce this themed collection of papers.

Graphical abstract: Engineering nanoparticles for sensing and biomedical applications: a themed collection
Review Article

Targeted drug delivery using iRGD peptide for solid cancer treatment

iRGD-mediated nanoparticle transcytosis in a solid tumor.

Graphical abstract: Targeted drug delivery using iRGD peptide for solid cancer treatment
From the themed collection: MDSE most-read Q2 2018
Review Article

Advancements on the molecular design of nanoantibiotics: current level of development and future challenges

Numerous antimicrobial drugs have been developed and commercialized to kill and inhibit the growth of pathogenic microbes.

Graphical abstract: Advancements on the molecular design of nanoantibiotics: current level of development and future challenges
From the themed collection: MDSE most-read Q2 2018
Communication

Degradable gold core–mesoporous organosilica shell nanoparticles for two-photon imaging and gemcitabine monophosphate delivery

The synthesis of degradable gold core–mesoporous organosilica shell nanoparticles is described.

Graphical abstract: Degradable gold core–mesoporous organosilica shell nanoparticles for two-photon imaging and gemcitabine monophosphate delivery
Paper

Monocore vs. multicore magnetic iron oxide nanoparticles: uptake by glioblastoma cells and efficiency for magnetic hyperthermia

PEGylated magnetic iron oxide nanoparticles (IONPs) were synthesised with the aim to provide proof of concept results of remote cancer cell killing by magnetic fluid hyperthermia.

Graphical abstract: Monocore vs. multicore magnetic iron oxide nanoparticles: uptake by glioblastoma cells and efficiency for magnetic hyperthermia
Paper

Modulating the catalytic activity of enzyme-like nanoparticles through their surface functionalization

Surface functional groups of nanozyme ligands dictate their kinetic behavior.

Graphical abstract: Modulating the catalytic activity of enzyme-like nanoparticles through their surface functionalization
From the themed collection: MSDE most-read Q3 2018
Paper

Design of SERS nanotags for multiplexed lateral flow immunoassays

Surface enhanced Raman spectroscopy (SERS) can be used to enhance the sensitivity of lateral flow immunoassays.

Graphical abstract: Design of SERS nanotags for multiplexed lateral flow immunoassays
Paper

Influence of mesopore size and peptide aggregation on the adsorption and release of a model antimicrobial peptide onto/from mesoporous silica nanoparticles in vitro

The interplay between mesopore size and degree of peptide aggregation controls both calcitonin adsorption onto and release from mesoporous silica nanoparticles.

Graphical abstract: Influence of mesopore size and peptide aggregation on the adsorption and release of a model antimicrobial peptide onto/from mesoporous silica nanoparticles in vitro
Paper

In vitro delivery of calcium ions by nanogated mesoporous silica nanoparticles to induce cancer cellular apoptosis

Calcium ions released by mesoporous silica nanoparticles taken up by cancer cells cause apoptosis.

Graphical abstract: In vitro delivery of calcium ions by nanogated mesoporous silica nanoparticles to induce cancer cellular apoptosis
From the themed collection: MDSE most-read Q2 2018
9 items

About this collection

From MSDE

Guest Edited by Professors Niveen M. Khashab (KAUST), Jean-Olivier Durand (Université de Montpellier) and Jeffrey I. Zink (UCLA), this collection showcases some of the major advances in engineering organic and inorganic nanosystems to develop superior biomedical materials.

Smart nanomaterials have taken the research and industry communities by storm, and the field of biomedical applications is no exception. The control of the nanoscale and physicochemical properties of particles, as well as the ability to visualize them via electron microscopy techniques and in cells, has ushered in numerous discoveries. In particular, stimuli-responsive or smart nanomaterials have unique advantages for bioimaging, sensing, and therapeutic applications.

The scale of nanomaterials can be precisely engineered towards specific applications. Stimuli-responsive nanoparticles have involved near-infrared light, magnetic, pH, enzymatic, and cascade actuations which have produced nano-platforms with higher selectivity and efficiency for their biomedical aim than previous nanomaterials.

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