Themed collection Omics in Animal Sciences
New approaches and omics tools for mining of vaccine candidates against vector-borne diseases
The availability of omics datasets coupled to high-throughput and bioinformatics analyses enabled rational and faster identification of new generation vaccine candidates.
Application of post-genomic techniques in dog cancer research
We present in this review the most recent achievement in the application of transcriptomics, proteomics and metabolomics to canine cancer research. The protocols to recover material suitable for omics analyses from formalin-fixed, paraffin-embedded tissues are highlighted, together with the potential of omics in veterinary cancer diagnostics.
High-throughput proteomics and the fight against pathogens
Pathogens pose a major threat to human and animal welfare. Understanding the interspecies host–pathogen protein–protein interactions could lead to the development of novel strategies to combat infectious diseases through the rapid development of new therapeutics.
The bovine milk microbiota: insights and perspectives from -omics studies
Recent findings and future perspectives of -omics studies on the bovine milk microbiota, focusing on its impact on animal health.
Omics approaches to probe markers of disease resistance in animal sciences
Disease pathways can be explained into a list of biomarkers at different scales to develop applications.
Immune relevant molecules identified in the skin mucus of fish using -omics technologies
This review will give an overview of immune relevant molecules in fish skin mucus.
Proteomics and the search for welfare and stress biomarkers in animal production in the one-health context
Stress and welfare are important factors in animal production in the context of growing production optimization and scrutiny by the general public.
Antibodies as stratagems against cancer
Antibodies have been in the frontline of anticancer research during the last few decades, since a number of different ways have been discovered to utilize them as parts or main components of anticancer drugs.
Regulation of highly homologous major urinary proteins in house mice quantified with label-free proteomic methods
We performed isoform-specific MUP quantification on MS1 and MS2 level in response to increased social interaction of male wild house mice by seminatural housing.
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics
Metabolomic investigation of milk from cows with bovine mastitis has revealed major changes in carbohydrates, lipids, amino acids, nucleotides and bile acids.
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics
Longitudinal proteomic analysis of bovine milk shows consistent changes over time across cows after intramammary challenge with Streptococcus uberis.
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics
Acute phase proteins and a group of 77 peptides in a biomarker panel increase in milk during bovine mastitis caused by a Streptococcus uberis infection of mammary glands.
Integrated data mining of transcriptomic and proteomic datasets to predict the secretome of adipose tissue and muscle in ruminants
Adipose tissue and muscle are endocrine organs releasing signalling and mediator proteins termed adipokines and myokines. The identification of the complete set of proteins secreted by adipose tissue and muscle is a challenge to understand the molecular cross-talk between these tissues and to reveal potential targets to control body or muscle composition and metabolism.
Increased intramuscular fat induced by reduced dietary protein in finishing pigs: effects on the longissimus lumborum muscle proteome
Reduced protein diets affects the amounts of proteins related to fibre type and structure and energy.
NMR-metabolomics profiling of mammary gland secretory tissue and milk serum in two goat breeds with different levels of tolerance to seasonal weight loss
Goats are of special importance in the Mediterranean and tropical regions for producing a variety of dairy products.
An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets
The rate of Flaviviridae family virus infections worldwide has increased dramatically in the last few years.
About this collection
Bringing together researchers taking advantage of the omics approach in the animal sciences and allied subjects this themed collection aims to integrate various omics expertise to help provide the “big picture” necessary to move towards unravelling the complexity of biological phenomena in the animal sciences.
This collection has been guest edited by Professors Mangesh Bhide, Fabrizio Ceciliani and Vladimir Mrljak.
New articles will be added to this collection as they are published.
Please return to this page frequently to see the collection grow.