Themed collection International Conference on Polyphenols and Health (ICPH2022) special collection
Can exosomes transfer the preconditioning effects triggered by (poly)phenol compounds between cells?
Exosomes direct and indirect roles mediating (poly)phenol effects.
Daily blueberry consumption for 12 weeks improves endothelial function in postmenopausal women with above-normal blood pressure through reductions in oxidative stress: a randomized controlled trial
This randomized, double-blind, placebo-controlled trial showed that blueberries improve endothelial function through reduced oxidative stress in postmenopausal women with above-normal blood pressure.
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice
CGA plus EGCG improve the gut barrier injury in aging mice induced by D-galactose through modulating the tight junctions, inflammation, oxidative stress and dysbiosis.
Walnut polyphenols and the active metabolite urolithin A improve oxidative damage in SH-SY5Y cells by up-regulating PKA/CREB/BDNF signaling
Walnut polyphenols and urolithin A up-regulate PKA/CREB/BDNF signaling pathway which is required for their neuroprotective effects against oxidative stress and may underlie their health benefits on the brain.
Plant-based dietary patterns and their association with mood in healthy individuals
Original Mediterranean Diet and Altered Mediterranean Diet were associated with positive mood when adjusted for sex and age in healthy people. Plant-based Diet Index was only associated with children’s positive mood.
Comparison between dietary assessment methods and biomarkers in estimating dietary (poly)phenol intake
This study compared the agreement between a food frequency questionnaire and a 7-day food diary in assessing (poly)phenol intake and explore their associations with the urinary and plasma (poly)phenol metabolites.
Improvements in gait and balance in patients with multiple sclerosis after treatment with coconut oil and epigallocatechin gallate. A pilot study
Multiple sclerosis (MS) is a neurodegenerative disease that progressively decreases the muscular and functional capacity.
The effects of a green Rooibos (Aspalathus linearis) extract on metabolic parameters and adipose tissue biology in rats fed different obesogenic diets
Supplementation with Rooibos extract modulated metabolic markers, adipocyte size and adipose stem cell (ASC) function in rats, under different dietary conditions. This is the first in vivo/ex vivo study to demonstrate effects of Rooibos on ASCs.
Saffron extract (Safr'Inside™) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites
Treatment of anxiety and depression predominantly centres around pharmacological interventions, which have faced criticism for their associated side effects, lack of efficacy and low tolerability.
Evening primrose seed extract rich in polyphenols modulates the invasiveness of colon cancer cells by regulating the TYMS expression
Natural polyphenols are plant metabolites exhibiting a broad range of biological activities.
Purified recombinant enzymes efficiently hydrolyze conjugated urinary (poly)phenol metabolites
Purified recombinant enzymes are efficient at hydrolyzing microbial (poly)phenol metabolite phase II conjugates, and hence, can be used to accurately quantify them using unconjugated analytical standards.
Cocoa flavanol consumption improves lower extremity endothelial function in healthy individuals and people with type 2 diabetes
T2DM individuals exhibit macro- and microvascular dysfunction that is pronounced in the legs. Cocoa acutely increases endothelial function of the brachial and the femoral arteries and dilation of microvasculature in the feet of T2DM and healthy individuals.
(−)-Epicatechin exerts positive effects on anxiety in high fat diet-induced obese mice through multi-genomic modifications in the hippocampus
(−)-Epicatechin exerts complex genomic modifications in the hippocampus, counteracting changes driven by consumption of the high fat diet and/or associated obesity.
Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo–in vitro colonic fermentation model
Upper tract gastrointestinal digestion unlocks the ability of cocoa and coffee bioactives to inhibit bacterial TMA formation.
Investigating the interaction between dietary polyphenols, the SARS CoV-2 spike protein and the ACE-2 receptor
In this contribution we show that 5-caffeoyl quinic acid reduces the affinity of the Coronavirus 2 Spike protein to the human ACE-2 receptor promising dietary prevention or slow-down of the SARS-CoC-2 pandemic.
Association between non-tea flavonoid intake and risk of type 2 diabetes: the Australian diabetes, obesity and lifestyle study
This study provides evidence that consuming flavonoid-rich food may be protective against type 2 diabetes (T2DM) through mechanisms related to better glucose tolerance and insulin sensitivity.
About this collection
In celebration of the International Conference on Polyphenols and Health (ICPH) 2022 which took place in London, UK, we are delighted to publish a Food & Function Special Collection to highlight the latest trends, topics and developments in the field of polyphenols, food science and health. This collection features relevant work from the conference participants, including speakers.