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Themed collection Peptide and protein nanotechnology

20 items
Editorial

Peptide and protein nanotechnology into the 2020s: beyond biology

Guest editors Rein Ulijn and Roman Jerala introduce the Peptide and protein nanotechnology themed issue of Chemical Society Reviews.

Graphical abstract: Peptide and protein nanotechnology into the 2020s: beyond biology
From the themed collection: Peptide and protein nanotechnology
Review Article

Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications

This article highlights the conformation-specific properties and functions of synthetic polypeptides derived from N-carboxyanhydrides.

Graphical abstract: Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications
From the themed collection: Peptide and protein nanotechnology
Review Article

Achieving biopolymer synergy in systems chemistry

Successful integration of chemical and physical networks through template assisted replication processes as well as mutualistic associations between polymers facilitates the translation of the macromolecular functions of biology into synthetic frameworks.

Graphical abstract: Achieving biopolymer synergy in systems chemistry
From the themed collection: Peptide and protein nanotechnology
Review Article

Guiding principles for peptide nanotechnology through directed discovery

This review explores recent efforts in the experimental and computational mapping and searching of the peptide sequence space, or directed discovery, of functional peptide based nanoscale systems and materials.

Graphical abstract: Guiding principles for peptide nanotechnology through directed discovery
From the themed collection: Peptide and protein nanotechnology
Review Article

Tailoring lumazine synthase assemblies for bionanotechnology

The cage-forming protein lumazine synthase is readily modified, evolved and assembled with other components.

Graphical abstract: Tailoring lumazine synthase assemblies for bionanotechnology
From the themed collection: Peptide and protein nanotechnology
Review Article

Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in material design

Nature is enriched with a wide variety of complex, synergistic and highly functional protein-based multicomponent assemblies.

Graphical abstract: Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in material design
From the themed collection: Peptide and protein nanotechnology
Review Article

Multicomponent peptide assemblies

This review presents recent efforts in the development of multicomponent supramolecular peptide assemblies with a focus on multicomponent assemblies derived from β-sheet peptides, low molecular weight peptides, peptide amphiphiles, coiled coil peptides, collagen, and related systems.

Graphical abstract: Multicomponent peptide assemblies
From the themed collection: Peptide and protein nanotechnology
Open Access Review Article

Molecular simulations of self-assembling bio-inspired supramolecular systems and their connection to experiments

The self-assembly of bio-inspired supramolecular polymers can be unravelled using molecular dynamics simulations combined with experiments.

Graphical abstract: Molecular simulations of self-assembling bio-inspired supramolecular systems and their connection to experiments
From the themed collection: Peptide and protein nanotechnology
Review Article

Solid-state electrical applications of protein and peptide based nanomaterials

This review summarizes recent advancements in electrical properties and applications of natural proteins and mutated variants, synthetic oligopeptides and peptide–π conjugates.

Graphical abstract: Solid-state electrical applications of protein and peptide based nanomaterials
From the themed collection: Peptide and protein nanotechnology
Review Article

Catalytic peptide assemblies

Peptides can self-assemble to form catalytic aggregates with activities comparable to those of natural enzymes.

Graphical abstract: Catalytic peptide assemblies
From the themed collection: Peptide and protein nanotechnology
Review Article

Peptide-based nanoprobes for molecular imaging and disease diagnostics

Peptide-based nanoprobes can improve the diagnosis, staging, treatment, management, and prognosis of numerous diseases by interfacing with and/or sensing of disease-relevant biomolecules.

Graphical abstract: Peptide-based nanoprobes for molecular imaging and disease diagnostics
From the themed collection: Peptide and protein nanotechnology
Review Article

Protein cage assembly across multiple length scales

Assembly of protein cages across multiple length scales is described, with an emphasis on their use as functional biomaterials.

Graphical abstract: Protein cage assembly across multiple length scales
From the themed collection: Peptide and protein nanotechnology
Review Article

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

Peptide– and protein–nanoparticle conjugates have emerged as powerful tools for biomedical applications, enabling the treatment, diagnosis, and prevention of disease.

Graphical abstract: Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications
From the themed collection: Peptide and protein nanotechnology
Review Article

The life of proteins under mechanical force

We review the role of mechanical force in the protein life cycle and give an outlook on mechanochemistry and mechanopharmacology.

Graphical abstract: The life of proteins under mechanical force
From the themed collection: Peptide and protein nanotechnology
Open Access Review Article

Coiled coil protein origami: from modular design principles towards biotechnological applications

This review illustrates the current state in designing coiled-coil-based proteins with an emphasis on coiled coil protein origami structures and their potential.

Graphical abstract: Coiled coil protein origami: from modular design principles towards biotechnological applications
From the themed collection: Peptide and protein nanotechnology
Tutorial Review

Silkworm silk-based materials and devices generated using bio-nanotechnology

Silks are natural fibrous protein polymers that are spun by silkworms and spiders. This tutorial review summarizes and highlights recent advances in the use of silkworm silk-based materials in bio-nanotechnology.

Graphical abstract: Silkworm silk-based materials and devices generated using bio-nanotechnology
From the themed collection: Peptide and protein nanotechnology
Tutorial Review

Engineering enzyme microenvironments for enhanced biocatalysis

Protein engineering provides a means to alter protein structure leading to new functions.

Graphical abstract: Engineering enzyme microenvironments for enhanced biocatalysis
From the themed collection: Peptide and protein nanotechnology
Tutorial Review

Protein delivery into cells using inorganic nanoparticle–protein supramolecular assemblies

Direct intracellular delivery of proteins using inorganic nanoparticle–protein supramolecular assemblies.

Graphical abstract: Protein delivery into cells using inorganic nanoparticle–protein supramolecular assemblies
From the themed collection: Peptide and protein nanotechnology
Tutorial Review

Minimalistic peptide supramolecular co-assembly: expanding the conformational space for nanotechnology

This review highlights the recent advances and future perspective of minimalistic peptide supramolecular co-assembly for nanotechnology.

Graphical abstract: Minimalistic peptide supramolecular co-assembly: expanding the conformational space for nanotechnology
From the themed collection: Peptide and protein nanotechnology
Open Access Tutorial Review

How should multicomponent supramolecular gels be characterised?

We discuss the current state of characterising multicomponent low molecular weight gels across all length scales, and the effectiveness of the different techniques that have been used.

Graphical abstract: How should multicomponent supramolecular gels be characterised?
From the themed collection: Peptide and protein nanotechnology
20 items

About this collection

We are delighted to present our Chemical Society Reviews themed issue on peptide and protein nanotechnology, guest edited by Rein V. Ulijn (CUNY) and Roman Jerala (National Institute of Chemistry, Ljubljana). Proteins and peptides are versatile programmable polymers and hold the key to fundamental working principles of biology. In the past decade there has been an expansion in the area, including a shift from designed structures to designed function, and this issue provides an overview of the state of this interdisciplinary field.

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