Guest editors Christopher J. Chang, Thorfinnur Gunnlaugsson and Tony D. James introduce the Imaging Agents issue of Chemical Society Reviews
Optical imaging probes for biomolecules: an introductory perspective
An overview of optical biomolecular imaging is provided.
Fluorescence imaging of metal ions implicated in diseases
This highlight discusses recent advances in fluorescent imaging of metal ions for understanding the role of metals in related diseases.
The development of ruthenium(II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications
A detailed overview of the development of Ru(II) polypyridyl complexes as diagnostic and therapeutic agents in vitro and in vivo.
Imaging agents based on lanthanide doped nanoparticles
This review summarizes the recent progress of single and multimodal imaging agents based on lanthanide doped nanoparticles.
Nanodiamonds and silicon quantum dots: ultrastable and biocompatible luminescent nanoprobes for long-term bioimaging
Ultra-stability and low-toxicity of silicon quantum dots and fluorescent nanodiamonds for long-term in vitro and in vivo bioimaging are demonstrated.
BODIPY-based probes for the fluorescence imaging of biomolecules in living cells
This review covers recent advances in the development of BODIPY-based fluorescent probes for biological studies.
Graphene-based nanomaterials for versatile imaging studies
This review highlights recent applications of graphene-based nanomaterials for various types of imaging studies.
Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors
Colourful cells and tissues: semiconductor quantum dots and their versatile applications in multiplexed bioimaging research.
Photoluminescence imaging of Zn2+ in living systems
Advances in PL imaging techniques, such as confocal microscopy, two photon microscopy, lifetime and optical imaging techniques, have made remarkable contributions in Zn2+ tracking.
Fluorometric imaging methods for palladium and platinum and the use of palladium for imaging biomolecules
Palladium and platinum metals have been used to facilitate novel bioimaging methods.
Luminescent probes for the bioimaging of small anionic species in vitro and in vivo
This comprehensive review examines recent developments in the use of fluorescent/luminescent probes for the bioimaging of anionic species. Images in cover art reproduced with permission from .
An overview of nanoparticles commonly used in fluorescent bioimaging
This article gives an overview of the various kinds of nanoparticles (NPs) that are widely used for purposes of fluorescent imaging, mainly of cells and tissues.
Using lanthanide ions in molecular bioimaging
This review presents an accessible discussion of the application of trivalent lanthanide ions in both optical and magnetic resonance imaging.
Soft fluorescent nanomaterials for biological and biomedical imaging
Various soft fluorescent nanomaterials based on organic chromophores are highly competent nano-probes for in vitro and in vivo imaging.
Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems
This review highlights progress in the development of molecular probes for live cell imaging of hydrogen sulfide and other reactive sulfur species, including sulfite, bisulfite, sulfane sulfur species, and S-nitrosothiols.
Carbon nanomaterials: multi-functional agents for biomedical fluorescence and Raman imaging
This review article gives a comparative overview over carbon nanomaterials utilized for in vitro as well as in vivo fluorescence and Raman imaging, including multi-functional theranostic approaches.
Silica-based nanoparticles: a versatile tool for the development of efficient imaging agents
In this review a selection of the most recent examples of imaging techniques applied to silica-based NPs for imaging is reported.
Fluorescent probes and bioimaging: alkali metals, alkaline earth metals and pH
This review highlights the recent advances that have been made in the design and bioimaging applications of fluorescent probes for alkali metals, alkaline earth metal cations and for pH determination within biological systems.
Recent advances in magnetic nanoparticle-based multi-modal imaging
This tutorial review discusses the concept and up-to-date applications of magnetic nanoparticle-based multi-modal imaging.
About this collection
This issue is part of a two-part themed issue series on Sensor Targets and Imaging Agents which has been guest edited by Chris Chang, Thorri Gunnlaugsson and Tony James. This themed issue on imaging agents will contain an exciting mix of reviews focussing on small organic or transition metal receptors. It will also include a selection of overview articles by leaders in the field, introducing each sub-topic of the issue; anions, metals, biomolecules/macromolecules, f-metal ion and materials. New articles will be added to this collection as they are published.