Themed collection Biomaterials Science Most Popular 2021

25 items
Review Article

Recent advances in near infrared light responsive multi-functional nanostructures for phototheranostic applications

NIR light-based theranostics become very crucial in the field of cancer nanomedicine. This review summarizes the recent advances of NIR light activatable multi-functional materials for cancer phototheranostics.

Graphical abstract: Recent advances in near infrared light responsive multi-functional nanostructures for phototheranostic applications
From the themed collection: Biomaterials Science Most Popular 2021
Review Article

Recent progress on nanomedicine-induced ferroptosis for cancer therapy

The basics of nanomedicine-based ferroptosis are summarized. The applications and future research directions of nanomedicine for ferroptosis-based anticancer therapy are presented.

Graphical abstract: Recent progress on nanomedicine-induced ferroptosis for cancer therapy
From the themed collection: Biomaterials Science Most Popular 2021
Review Article

Recent trends on burn wound care: hydrogel dressings and scaffolds

Biomaterial -based therapy in burn wound care and the roles and advantages of hydrogels.

Graphical abstract: Recent trends on burn wound care: hydrogel dressings and scaffolds
From the themed collection: Biomaterials Science Most Popular 2021
Open Access Review Article

Biomimetic hydrogels designed for cartilage tissue engineering

Cartilage-like hydrogels based on materials like gelatin, chondroitin sulfate, hyaluronic acid and polyethylene glycol are reviewed and contrasted, revealing existing limitations and challenges on biomimetic hydrogels for cartilage regeneration.

Graphical abstract: Biomimetic hydrogels designed for cartilage tissue engineering
From the themed collection: Biomaterials Science Most Popular 2021
Review Article

Advances of hydrogel dressings in diabetic wounds

The hydrogel dressings with various functions for diabetic wound treatment.

Graphical abstract: Advances of hydrogel dressings in diabetic wounds
From the themed collection: Biomaterials Science Most Popular 2021
Review Article

Cell-penetrating peptides (CPPs): an overview of applications for improving the potential of nanotherapeutics

Restricted entry into the cells stands as an ultimate challenge for nanotherapeutics to exhibit their efficacy. Cell penetrating peptides can act as a crucial assistant for overcoming this challenge.

Graphical abstract: Cell-penetrating peptides (CPPs): an overview of applications for improving the potential of nanotherapeutics
From the themed collection: Biomaterials Science Most Popular 2021
Communication

Biofilm inhibition in oral pathogens by nanodiamonds

Nanodiamonds were demonstrated to have great effects on inhibiting biofilm formation as well as disrupting the preformed biofilm in several selected orally and systemically important organisms.

Graphical abstract: Biofilm inhibition in oral pathogens by nanodiamonds
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Enhanced anti-tumor efficacy by inhibiting HIF-1α to reprogram TAMs via core-satellite upconverting nanoparticles with curcumin mediated photodynamic therapy

Cur–CSNPs mediated PDT suppress TNBC through the synergistic immunotherapeutic effects by suppressing the expression of HIF-1α to reprogram the pro-tumor TAM2 into the anti-tumor TAM1.

Graphical abstract: Enhanced anti-tumor efficacy by inhibiting HIF-1α to reprogram TAMs via core-satellite upconverting nanoparticles with curcumin mediated photodynamic therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Alginate/chitosan-based hydrogel loaded with gene vectors to deliver polydeoxyribonucleotide for effective wound healing

The prepared polydeoxyribonucleotide (PDRN)-loaded alginate/chitosan-based hydrogel as a “nanocomposite smart material” combines the advantages of gene vectors and hydrogels and promotes the wound healing process.

Graphical abstract: Alginate/chitosan-based hydrogel loaded with gene vectors to deliver polydeoxyribonucleotide for effective wound healing
From the themed collection: Biomaterials Science Most Popular 2021
Open Access Paper

Gene activated scaffolds incorporating star-shaped polypeptide-pDNA nanomedicines accelerate bone tissue regeneration in vivo

Gene activated scaffolds incorporating star-shaped polypeptide-pDNA nanomedicines accelerate bone tissue regeneration in vivo.

Graphical abstract: Gene activated scaffolds incorporating star-shaped polypeptide-pDNA nanomedicines accelerate bone tissue regeneration in vivo
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Encapsulating an acid-activatable phthalocyanine–doxorubicin conjugate and the hypoxia-sensitive tirapazamine in polymeric micelles for multimodal cancer therapy

A multicomponent nanodrug based on polymeric micelles has been fabricated and examined for its potential in combined photodynamic therapy, chemotherapy and hypoxia-activated therapy of cancer.

Graphical abstract: Encapsulating an acid-activatable phthalocyanine–doxorubicin conjugate and the hypoxia-sensitive tirapazamine in polymeric micelles for multimodal cancer therapy
From the themed collection: Biomaterials Science Most Popular 2021
Paper

3D bio-printed biphasic scaffolds with dual modification of silk fibroin for the integrated repair of osteochondral defects

Repair of osteochondral defects is still a challenge, especially the regeneration of hyaline cartilage.

Graphical abstract: 3D bio-printed biphasic scaffolds with dual modification of silk fibroin for the integrated repair of osteochondral defects
From the themed collection: Biomaterials Science Most Popular 2021
Paper

An injectable and biodegradable nano-photothermal DNA hydrogel enhances penetration and efficacy of tumor therapy

Injectable and biodegradable DNA gel nanoparticles with a controllable charge and size as a photothermal therapeutic agent improve the permeability of drugs, reduce drug resistance, and improve the survival rate of mice.

Graphical abstract: An injectable and biodegradable nano-photothermal DNA hydrogel enhances penetration and efficacy of tumor therapy
From the themed collection: Biomaterials Science Most Popular 2021
Open Access Paper

Encapsulating bacteria in alginate-based electrospun nanofibers

We developed GRAS nanofibers for the delivery of viable bacteria into the gut. Model bacterium were encapsulated in alginate-based nanofibers via electrospinning and a bacteria loading of 2.74 × 105 CFU g−1 of mat was achieved.

Graphical abstract: Encapsulating bacteria in alginate-based electrospun nanofibers
Paper

Milk exosomes with enhanced mucus penetrability for oral delivery of siRNA

High-purity milk exosomes were engineered with surface PEGylation and siRNA encapsulation for enhanced oral drug delivery.

Graphical abstract: Milk exosomes with enhanced mucus penetrability for oral delivery of siRNA
From the themed collection: Biomaterials Science Most Popular 2021
Paper

A chondroitin sulfate based injectable hydrogel for delivery of stem cells in cartilage regeneration

An injectable hydrogel system fabricated with functionalised chondroitin sulfate and a hyperbranched multi-functional PEG polymer was developed as a stem cell delivery system for cartilage tissue engineering.

Graphical abstract: A chondroitin sulfate based injectable hydrogel for delivery of stem cells in cartilage regeneration
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Injectable keratin hydrogels as hemostatic and wound dressing materials

A protein-based injectable hydrogel was prepared in a convenient way and applied for biomedical applications as hemostatic and wound dressing materials.

Graphical abstract: Injectable keratin hydrogels as hemostatic and wound dressing materials
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Aligned and electrically conductive 3D collagen scaffolds for skeletal muscle tissue engineering

We introduce a scaffold combining 3D structural alignment and electrical conductivity for skeletal muscle tissue engineering. We show that aligned and conductive scaffolds support myoblast viability, 3D alignment, and early myotube formation.

Graphical abstract: Aligned and electrically conductive 3D collagen scaffolds for skeletal muscle tissue engineering
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Engineering 3D-printed core–shell hydrogel scaffolds reinforced with hybrid hydroxyapatite/polycaprolactone nanoparticles for in vivo bone regeneration

3D-printed biphasic core/shell hydrogel scaffolds with hybrid bioactive nanoparticles reinforcing core phase possessed controlled swelling, mechanical stiffness and dual-ranged pore size. They provided prominent osteoconductivity, biocompatibility and in-vivo osteogenicity.

Graphical abstract: Engineering 3D-printed core–shell hydrogel scaffolds reinforced with hybrid hydroxyapatite/polycaprolactone nanoparticles for in vivo bone regeneration
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Engineering of biofilms with a glycosylation circuit for biomaterial applications

Glycosylation can be a promising tool for engineering protein-based biomaterials specifically regarding adhesion.

Graphical abstract: Engineering of biofilms with a glycosylation circuit for biomaterial applications
From the themed collection: Biomaterials Science Most Popular 2021
Open Access Paper

Mechanical properties of cell- and microgel bead-laden oxidized alginate-gelatin hydrogels

Cell containing hydrogels represent a key strategy in tissue engineering. Complex mechanical analyses show that the stiffness significantly drops for high concentrations of cells and microgel-bead fillers in non-fibrous alginate-based hydrogels.

Graphical abstract: Mechanical properties of cell- and microgel bead-laden oxidized alginate-gelatin hydrogels
From the themed collection: Biomaterials Science Most Popular 2021
Open Access Paper

In vivo soft tissue reinforcement with bacterial nanocellulose

The biopolymer bacterial nanocellulose presents attractive mechanical and anti-adherent properties for innovative hernia repair solutions.

Graphical abstract: In vivo soft tissue reinforcement with bacterial nanocellulose
From the themed collection: Biomaterials Science Most Popular 2021
Paper

3D bioprinting dermal-like structures using species-specific ulvan

3D cellularized structures revealing dermal-like properties have been successfully printed using bioinks based on the sulfated polysaccharide ulvan from Australian green seaweed.

Graphical abstract: 3D bioprinting dermal-like structures using species-specific ulvan
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Molecular mobility of polyrotaxane-based biointerfaces alters inflammatory responses and polarization in Kupffer cell lines

Molecular mobility of polyrotaxane-based biointerfaces altered the cellular morphology and gene expression of pro-inflammatory cytokines in the presence of lipopolysaccharide.

Graphical abstract: Molecular mobility of polyrotaxane-based biointerfaces alters inflammatory responses and polarization in Kupffer cell lines
From the themed collection: Biomaterials Science Most Popular 2021
Paper

Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices

This work provides microenvironmental design parameters to optimize iPSC-cardiomyocyte tissues formed on tunable synthetic matrices that mimic myocardial ECM.

Graphical abstract: Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices
From the themed collection: Biomaterials Science Most Popular 2021
25 items

About this collection

This online collection features some of the most cited, most downloaded and most shared articles published in Biomaterials Science during 2021.
Thank you to our authors, reviewers and readers for your ongoing support.

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