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Themed collection Highlighting analytical science in France, Italy and Spain

19 items
Tutorial Review

AFM, SECM and QCM as useful analytical tools in the characterization of enzyme-based bioanalytical platforms

A review of the use of AFM, SECM and QCM as analytical tools in the characterization of enzyme-based bioanalytical platforms is presented.

Graphical abstract: AFM, SECM and QCM as useful analytical tools in the characterization of enzyme-based bioanalytical platforms
Critical Review

Homogeneous assays using aptamers

This review is the first entirely dedicated to aptamer- and aptazyme-based homogeneous assays carried out in a solution phase.

Graphical abstract: Homogeneous assays using aptamers
Critical Review

Plasma-based mass spectrometry for simultaneous acquisition of elemental and molecular information

Recent developments in plasma-based mass spectrometric instrumentation for integrated (elemental and molecular) chemical speciation studies are presented.

Graphical abstract: Plasma-based mass spectrometry for simultaneous acquisition of elemental and molecular information
Critical Review

Fourier transform mass spectrometry for metabolome analysis

We evaluate the improvements provided for metabolomics by different types of FT/MS instruments, together with the ability of these platforms to cover the various analytical requirements of metabolomics.

Graphical abstract: Fourier transform mass spectrometry for metabolome analysis
Critical Review

Intracellular magnesium detection: imaging a brighter future

The state of the art and future developments in intracellular magnesium detection by fluorescent sensors and live imaging are discussed.

Graphical abstract: Intracellular magnesium detection: imaging a brighter future
Paper

Functionalization of single-walled carbon nanotubes for direct and selective electrochemical detection of DNA

Hybridization of the complementary DNA sequence breaks interactions between the redox probe and the DNA probe, which speeds-up electron transfer.

Graphical abstract: Functionalization of single-walled carbon nanotubes for direct and selective electrochemical detection of DNA
Paper

Study of the capillary electrophoresis profile of intact α-1-acid glycoprotein isoforms as a biomarker of atherothrombosis

Statistical analysis shows that the CE profile of intact AGP purified by immunoaffinity chromatography from plasma is a potential biomarker of atherothrombosis.

Graphical abstract: Study of the capillary electrophoresis profile of intact α-1-acid glycoprotein isoforms as a biomarker of atherothrombosis
Paper

New nanostructured electrochemical biosensors based on three-dimensional (3-mercaptopropyl)-trimethoxysilane network

Electrochemical response and morphological characterization by SEM and AFM of a new nanostructured biosensor based on three-dimensional (3-mercaptopropyl)-trimethoxysilane network.

Graphical abstract: New nanostructured electrochemical biosensors based on three-dimensional (3-mercaptopropyl)-trimethoxysilane network
Paper

Opto-electrochemical nanosensor array for remote DNA detection

A high-density array of opto-electrochemical nanosensors is presented for remote DNA detection through a nanostructured optical fiber bundle.

Graphical abstract: Opto-electrochemical nanosensor array for remote DNA detection
Paper

DNA hybridization induced selective encapsulation of small dye molecules in dendrimer based microcapsules

A novel approach for selectively encapsulating Cy5 dye molecules via DNA hybridization in cationic phosphorus dendrimers (G4+)/polystyrenesulfonate (PSS) microcapsules has been developed.

Graphical abstract: DNA hybridization induced selective encapsulation of small dye molecules in dendrimer based microcapsules
Paper

In situ identification and imaging of bacterial polymer nanogranules by infrared nanospectroscopy

The AFM-IR technique using an IR laser and AFM is a tool suited to chemical analysis at the nanometric scale. The identification and imaging of 50–400 nm size polyhydroxybutyrate (PHB) granules inside a single Rhodobacter capsulatus bacterium illustrate the exciting potentiality of this new photothermal near-field technique.

Graphical abstract: In situ identification and imaging of bacterial polymer nanogranules by infrared nanospectroscopy
Paper

Ultrasensitive optical detection of hydrogen peroxide by triggered activation of horseradish peroxidase

Reconstitution of hemin di(N,N′-acetylhydrazide) with apo horseradish peroxidase and hydrogen peroxide for the ultra-sensitive detection of H2O2 and glucose oxidase.

Graphical abstract: Ultrasensitive optical detection of hydrogen peroxide by triggered activation of horseradish peroxidase
Paper

Viable route for switching of an engineered silica surface using Cu2+ ions at sub-ppm levels

The novel monolayer architecture allows specific reversible switching between two states using Cu2+ ions as input and the absorbance intensity as output. Switching is straightforward and the optical read-out fast.

Graphical abstract: Viable route for switching of an engineered silica surface using Cu2+ ions at sub-ppm levels
Paper

Disposable immunosensor for cortisol using functionalized magnetic particles

A novel electrochemical immunosensor using screen-printed carbon electrodes and functionalized magnetic particles was developed for the determination of cortisol.

Graphical abstract: Disposable immunosensor for cortisol using functionalized magnetic particles
Paper

Influence of cell geometry and number of replicas in the reproducibility of whole cell FTIR analysis

This paper shows for the first time the effects of cell shape and dimensions on the spectra quality and variability.

Graphical abstract: Influence of cell geometry and number of replicas in the reproducibility of whole cell FTIR analysis
Paper

Non-linear multivariate curve resolution analysis of voltammetric pH titrations

Non-linearity correction in voltammetric pH titrations using shape constraints for modelling the shifts in peak potentials.

Graphical abstract: Non-linear multivariate curve resolution analysis of voltammetric pH titrations
Paper

Screen-printed microsystems for the ultrasensitive electrochemical detection of alkaline phosphatase

The fabrication of a low cost, easy to manufacture microsystem and its application to achieve ultrasensitive electrochemical detection of alkaline phosphatase is herein described.

Graphical abstract: Screen-printed microsystems for the ultrasensitive electrochemical detection of alkaline phosphatase
Paper

Polymers with embedded chemical indicators as an artificial olfactory mucosa

Olfactory mucosa inspired a novel approach to chemical sensors. The concept is demonstrated with two polymer layers embedded with a chemical indicator. Multivariate analysis illustrates the synergy of polymer and indicator properties.

Graphical abstract: Polymers with embedded chemical indicators as an artificial olfactory mucosa
Paper

Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings

Ion insertion solid state electrochemistry is used to determine the amount of phenethylamine, dopamine, homoveratrylamine, mescaline, (±)-amphetamine, (±)-p-methoxyamphetamine, and (±)-methamphetamine in aqueous media with high selectivity.

Graphical abstract: Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings
19 items

About this collection

Analyst has collected together some of the latest exciting research published in the journal from researchers working in France, Italy and Spain. Read the highlighted articles in this web themed issue, which has been guest edited by José Pingarrón (Complutense University of Madrid, Spain) and Serge Cosnier (Université Joseph Fourier, France).

Spotlight

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