Electrochemical oxidative dehydrogenative annulation of 1-(2-aminophenyl)pyrroles with cleavage of ethers to synthesize pyrrolo[1,2-a]quinoxaline derivatives

Abstract

An array of pyrrolo[1,2-a]quinoxaline derivatives were achieved with moderate to good yields via the electrochemical redox reaction, which includes the functionalization of C(sp³)–H bonds and the construction of C–C and C–N bonds. In this atom economic reaction, THF was used as both a reactant and a solvent, and H₂ was the sole by-product.