Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent materials

Ya-Fang Xiao; Jia-Xiong Chen; Wen-Cheng Chen; Xiuli Zheng; Chen Cao; Jihua Tan; Xiao Cui; Zhanxiang Yuan; Shaomin Ji; Guihong Lu; Weimin Liu; Pengfei Wang; Shengliang Li; Chun-Sing Lee

doi:10.1039/D0CC08323B

Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent materials†

Ya-Fang Xiao,

^ab Jia-Xiong Chen,

^ab Wen-Cheng Chen,

*^c Xiuli Zheng,

^bd Chen Cao,^ab Jihua Tan,^ab Xiao Cui,^ab Zhanxiang Yuan,^c Shaomin Ji,

^c Guihong Lu,*^e Weimin Liu,

^bd Pengfei Wang,

^bd Shengliang Li

*^ab and Chun-Sing Lee

*^ab

Author affiliations

* Corresponding authors

^a Center of Super-Diamond and Advanced Films (COSDAF) and Department of Chemistry, City University of Hong Kong, Hong Kong, P. R. China
E-mail: apcslee@cityu.edu.hk

^b Joint Laboratory of Nano-Organic Functional Materials and Devices (TIPC and CityU), City University of Hong Kong, Kowloon, Hong Kong SAR, P. R. China

^c School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, P. R. China

^d Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China

^e State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, 1 North 2nd Street, Zhong Guan Cun, Beijing 100190, China

Abstract

A bromine-substituted thermally activated delayed fluorescent (TADF) molecule AQCzBr₂ is designed with both small singlet–triplet splitting (ΔE_ST) and increased spin–orbit coupling (SOC) to boost intersystem crossing (ISC) for singlet oxygen generation. AQCzBr₂ nanoparticles (NPs) demonstrate high productivity of singlet oxygen generation (Φ_Δ = 0.91) which allows highly efficient photodynamic therapy toward cancer cells.

Chemical Communications

Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent materials†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent materials

Social activity

Search articles by author

Spotlight

Advertisements