Issue 93, 2015

In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

Abstract

Labelling of proteins with a luminescent ruthenium complex enables the direct visualization and photocatalytic reduction of aryl azide in live cells. The confinement of catalysis to the labeled proteins was visualized using an azide-based immolative linker releasing a precipitating dye.

Graphical abstract: In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

Supplementary files

Article information

Article type
Communication
Submitted
01 Jul 2015
Accepted
24 Sep 2015
First published
24 Sep 2015

Chem. Commun., 2015,51, 16664-16666

In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

K. K. Sadhu, E. Lindberg and N. Winssinger, Chem. Commun., 2015, 51, 16664 DOI: 10.1039/C5CC05405B

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