Issue 22, 1993

Synthesis of racemic myo-inositol 1,4,5-trisphosphate 3-O-methylenecarboxylate, a Ca2+-mobilising myo-lnositol 1,3,4,5-tetrakisphosphate analogue

Abstract

Synthesis of a biologically potent inositol polyphosphate analogue, myo-inositol 1,4,5-triphosphate-3-O-methylene carboxylate incorporating an efficient oxidative cleavage of an O-allyl ether in the presence of protected phosphate triesters is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1993, 1687-1689

Synthesis of racemic myo-inositol 1,4,5-trisphosphate 3-O-methylenecarboxylate, a Ca2+-mobilising myo-lnositol 1,3,4,5-tetrakisphosphate analogue

C. Liu, N. F. Thomas and B. V. L. Potter, J. Chem. Soc., Chem. Commun., 1993, 1687 DOI: 10.1039/C39930001687

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