Issue 26, 2015
From the journal:

RSC Advances

Delivery of SiC-based nanoparticles into live cells driven by cell-penetrating peptides SAP and SAP-E†

T. Serdiuk,ab   I. Bakanovich,c   V. Lysenko,d   S. A. Alekseev,b   V. A. Skryshevsky,b   S. Afonin,e   E. Berger,a   A. Géloëna  and  I. V. Komarov*b  

* Corresponding authors

a University of Lyon, CarMeN Laboratory, INSA de Lyon, UMR INSERM 1060, France

b Taras Shevchenko National University of Kyiv, Volodymyrs`ka 64, 01601 Kyiv, Ukraine
E-mail: ik214@yahoo.com

c Enamine Ltd, Matrosova 23, 01103 Kyiv, Ukraine

d University of Lyon, Nanotechnology Institute of Lyon (INL), INSA de Lyon, UMR CNRS 5270, France

e Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology, POB 3640, 76021 Karlsruhe, Germany

Abstract

The delivery of SiC-based nanoparticles (SiC-NPs) into living eukaryotic cells is facilitated in the presence of cell-penetrating peptides, both cationic (SAP) and anionic (SAP-E). The SiC-NP surface functional group modification combined with rational CPP selection introduces an additional mode of delivery control.

Graphical abstract: Delivery of SiC-based nanoparticles into live cells driven by cell-penetrating peptides SAP and SAP-E

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Article information

DOI
https://doi.org/10.1039/C4RA10688A
Article type
Communication
Submitted
18 Sep 2014
Accepted
05 Feb 2015
First published
06 Feb 2015

RSC Adv., 2015,5, 20498-20502

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Delivery of SiC-based nanoparticles into live cells driven by cell-penetrating peptides SAP and SAP-E

T. Serdiuk, I. Bakanovich, V. Lysenko, S. A. Alekseev, V. A. Skryshevsky, S. Afonin, E. Berger, A. Géloën and I. V. Komarov, RSC Adv., 2015, 5, 20498 DOI: 10.1039/C4RA10688A

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