I2-catalyzed oxidative C(sp3)–H/S–H coupling: utilizing alkanes and mercaptans as the nucleophiles†
Abstract
By using alkanes and mercaptans as the nucleophiles with di-tert-butyl peroxide (DTBP) as the oxidant, I2-catalyzed oxidative C(sp3)–H/S–H coupling was achieved. This protocol provides a novel process to construct C(sp3)–S bonds from commercially available hydrocarbons and mercaptans.