An efficient synthetic method for preparing novel 1-allyl-6-(1′,2′,3′-triazolyl) analogues of HEPT, an anti-HIV reverse transcriptase inhibitor, is reported. The key step is based upon selective intermolecular cycloaddition of azide to acetylenes.
P. J. Bhuyan, H. N. Borah and J. S. Sandhu, J. Chem. Soc., Perkin Trans. 1, 1999, 3083 DOI: 10.1039/A906222J
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