Issue 21, 1999

Studies on uracils: an efficient method for the synthesis of novel 1-allyl-6-(1′,2′,3′-triazolyl) analogues of HEPT

Abstract

An efficient synthetic method for preparing novel 1-allyl-6-(1′,2′,3′-triazolyl) analogues of HEPT, an anti-HIV reverse transcriptase inhibitor, is reported. The key step is based upon selective intermolecular cycloaddition of azide to acetylenes.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1999, 3083-3084

Studies on uracils: an efficient method for the synthesis of novel 1-allyl-6-(1′,2′,3′-triazolyl) analogues of HEPT

P. J. Bhuyan, H. N. Borah and J. S. Sandhu, J. Chem. Soc., Perkin Trans. 1, 1999, 3083 DOI: 10.1039/A906222J

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