Nanoparticle-in-Microparticle Oral Delivery System Based on Drug-Loaded Polymeric Micelles

Abstract

This work develops and characterises a hierachichal oral drug delivery system based on the microencapsulation of drug-loaded amphiphilic nanogels within a mucoadhesive alginate/chitosan shell. Results show a more controlled release and a statistically significant oral half-life with respect to the free drug.

Supplementary files

Article information

Article type
Communication
Submitted
16 Feb 2026
Accepted
08 Apr 2026
First published
17 Apr 2026
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2026, Accepted Manuscript

Nanoparticle-in-Microparticle Oral Delivery System Based on Drug-Loaded Polymeric Micelles

H. Moshe Halamish, R. Sverdlov Arzi and A. Sosnik, Chem. Commun., 2026, Accepted Manuscript , DOI: 10.1039/D6CC01038E

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