Structural mechanisms of cellulose-based nanocomposites mimicking the structure of articular cartilage under uniaxial compression probed by in situ SAXS

Fanny Bosson; Mohamed Karrouch; Didier Blésès; William Chèvremont; Thomas Gibaud; Laurent Michot; Bruno Jean; Vianney Delplace; Nicolas Hengl; Frédéric Pignon

doi:10.1039/D5NR01942G

Structural mechanisms of cellulose-based nanocomposites mimicking the structure of articular cartilage under uniaxial compression probed by in situ SAXS

Fanny Bosson,^a Mohamed Karrouch,^a Didier Blésès,^a William Chèvremont,

^b Thomas Gibaud,

^c Laurent Michot,

^d Bruno Jean,

^e Vianney Delplace,

^f Nicolas Hengl^a and Frédéric Pignon

*^a

Author affiliations

* Corresponding authors

^a Univ. Grenoble Alpes, CNRS, Grenoble INP (Institute of Engineering Univ. Grenoble Alpes), LRP, F-38000 Grenoble, France
E-mail: frederic.pignon@univ-grenoble-alpes.fr

^b ESRF, The European Synchrotron, F-38043 Grenoble, France

^c Univ Lyon, ENS de Lyon, Univ Claude Bernard, CNRS, Laboratoire de Physique, F-69342 Lyon, France

^d Sorbonne Université, CNRS, Physicochimie des Electrolytes et Nanosystèmes Interfaciaux, PHENIX, F-75005 Paris, France

^e Univ. Grenoble Alpes, CNRS, CERMAV, Grenoble, France

^f Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, F-44000 Nantes, France

Abstract

A new method combining frontal ultrafiltration and ultrasound, followed by UV photocrosslinking enabled the fabrication of orthotropic CNC/PEGDA (poly(ethylene glycol) diacrylate) nanocomposites with the structure of articular cartilage. In situ SAXS compression/relaxation mechanical tests demonstrated this orthotropic organization as well as elastic behavior with a Young's modulus of 0.76 MPa, similar to articular cartilage.

Nanoscale

Structural mechanisms of cellulose-based nanocomposites mimicking the structure of articular cartilage under uniaxial compression probed by in situ SAXS

Abstract

Supplementary files

Transparent peer review

Article information

Download Citation

Permissions

Structural mechanisms of cellulose-based nanocomposites mimicking the structure of articular cartilage under uniaxial compression probed by in situ SAXS

Social activity

Search articles by author

Spotlight

Advertisements