Motion of microswimmers in cylindrical microchannels

Abstract

Biological and artificial microswimmers often have to propel through a variety of environments, ranging from heterogeneous suspending media to strong geometrical confinement. Under confinement, local flow fields generated by microswimmers, and steric and hydrodynamic interactions with their environment determine the locomotion. We propose a squirmer-like model to describe the motion of microswimmers in cylindrical microchannels, where propulsion is generated by a fixed surface slip velocity. The model is studied using an approximate analytical solution for cylindrical swimmer shapes, and by numerical hydrodynamics simulations for spherical and spheroidal shapes. For the numerical simulations, we employ the dissipative particle dynamics method for modelling fluid flow. Both the analytical model and simulations show that the propulsion force increases with increasing confinement. However, the swimming velocity under confinement remains lower than the swimmer speed without confinement for all investigated conditions. In simulations, different swimming modes (i.e. pusher, neutral, puller) are investigated, and found to play a significant role in the generation of propulsion force when a swimmer approaches a dead end of a capillary tube. Propulsion generation in confined systems is local, such that the generated flow field generally vanishes beyond the characteristic size of the swimmer. These results contribute to a better understanding of microswimmer force generation and propulsion under strong confinement, including the motion in porous media and in narrow channels.