Issue 8, 2024

Rhodium-catalyzed C–C bond alkenylation and arylation of α-branched N-sulfonyl amines

Abstract

This work demonstrates rhodium-catalyzed C–C bond cleavage of α-branched primary amines via β-carbon elimination. A pyridinyl group is employed to stabilize the rhodacycle intermediate, which subsequently undergoes either alkenylation with olefins or arylation with silane reagents. This novel protocol incorporates a broad range of both amines and coupling partners by utilizing cyclopentadienyl-type ligands.

Graphical abstract: Rhodium-catalyzed C–C bond alkenylation and arylation of α-branched N-sulfonyl amines

Supplementary files

Article information

Article type
Research Article
Submitted
02 Jan 2024
Accepted
18 Feb 2024
First published
21 Feb 2024

Org. Chem. Front., 2024,11, 2182-2188

Rhodium-catalyzed C–C bond alkenylation and arylation of α-branched N-sulfonyl amines

L. Xu, Y. Liu, H. Shi and L. Li, Org. Chem. Front., 2024, 11, 2182 DOI: 10.1039/D3QO02140H

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