Recent progress in the synthesis of pyrrolo[2,1-a]isoquinolines

Abstract

Pyrrolo[2,1-a]isoquinolines occur frequently in a large number of bioactive natural products and pharmaceutically important molecules. The synthesis of pyrrolo[2,1-a]isoquinoline derivatives is an easy and useful way to produce artificial molecules with potential applications. A huge number of excellent methodologies for constructing pyrrolo[2,1-a]isoquinolines have been reported in the last decade. This review summarizes the recent advances in this research field covering from 2011 to 2021.