Mahesh H. Shinde and Chepuri V. Ramana
Org. Biomol. Chem., 2022,20, 2086-2095
DOI:
10.1039/D1OB02483C,
Paper
A simple approach for the synthesis of pyridoindolone scaffolds with a spiroannulated tetrahydrofuran ring is described. The overall process comprises intramolecular sequential gold-catalysed 5-endo-dig alkynol cycloisomerization and subsequent addition of indole C2 to the in situ generated oxocarbenium cation.