Issue 74, 2022
From the journal:

Chemical Communications

A novel furo[3,2-c]pyridine-based AIE photosensitizer for specific imaging and photodynamic ablation of Gram-positive bacteria†

Ming-Yu Wu, ORCID logo *a   Yun Wang,a   Li-Juan Wang,a   Jia-Li Wang,a   Feng-Wei Xiaa  and  Shun Feng*a  

* Corresponding authors

a Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China
E-mail: wumy1050hx@swjtu.edu.cn, fengshun@swjtu.edu.cn

Abstract

An Rh-catalyzed tandem reaction was performed to construct an AIE-active furo[2,3-c]pyridine-based photosensitizer, named LIQ-TF. LIQ-TF showed near-infrared emission with high quantum yield, and high 1O2 and ˙OH generation efficiency, and could be used for specific imaging and photodynamic ablation of Gram-positive bacteria in vitro and in vivo, showing great potential for combating multiple drug-resistant bacteria.

Graphical abstract: A novel furo[3,2-c]pyridine-based AIE photosensitizer for specific imaging and photodynamic ablation of Gram-positive bacteria

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D2CC04084K
Article type
Communication
Submitted
21 Jul 2022
Accepted
19 Aug 2022
First published
19 Aug 2022

Chem. Commun., 2022,58, 10392-10395

Permissions

Request permissions

A novel furo[3,2-c]pyridine-based AIE photosensitizer for specific imaging and photodynamic ablation of Gram-positive bacteria

M. Wu, Y. Wang, L. Wang, J. Wang, F. Xia and S. Feng, Chem. Commun., 2022, 58, 10392 DOI: 10.1039/D2CC04084K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements