Zhenyu Sun, Guanghui Ji, Guoli Wang, Lei Wei, Ying Zhang and Haojie Lu
Chem. Commun., 2021,57, 4154-4157
DOI:
10.1039/D1CC00197C,
Communication
Here, we have developed an approach termed methylamine stable isotope labeling (MeSIL) to relatively quantify N-glycopeptides through one step labeling. It is the first time that this approach is applied to measure N-glycopeptide changes in huh7 cells after Zika virus infection and it has been revealed that differentially expressed N-glycopeptides played important roles in virus infection at the glycosylation site-specific level.