Issue 5, 2021

Azide–alkyne cycloadditions in a vortex fluidic device: enhanced “on water” effects and catalysis in flow

Abstract

The Vortex Fluidic Device is a flow reactor that processes reactions in thin films. Running the metal-free azide–alkyne cycloaddition in this reactor revealed a dramatic enhancement of the “on water” effect. For the copper-catalyzed azide–alkyne cycloaddition, stainless steel or copper jet feeds were effective reservoirs of active copper catalyst.

Graphical abstract: Azide–alkyne cycloadditions in a vortex fluidic device: enhanced “on water” effects and catalysis in flow

Supplementary files

Article information

Article type
Communication
Submitted
25 Jun 2020
Accepted
10 Dec 2020
First published
14 Dec 2020

Chem. Commun., 2021,57, 659-662

Azide–alkyne cycloadditions in a vortex fluidic device: enhanced “on water” effects and catalysis in flow

G. Oksdath-Mansilla, R. L. Kucera, J. M. Chalker and C. L. Raston, Chem. Commun., 2021, 57, 659 DOI: 10.1039/D0CC04401F

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