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Issue 31, 2020
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Gold-catalyzed enantioselective functionalization of indoles

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Abstract

Gold catalysis and indole chemistry are two mature and prolific fields. The gold-catalyzed functionalization of indoles has produced numerous results and paved the way for novel strategies in the building of molecular complexity. However – and curiously – though enantioselective gold catalysis is now a well-established field, it has been relatively little applied to the modification of indoles. This review highlights most of the enantioselective gold-catalyzed examples of the functionalization of indoles in order to emphasize the strengths and limitations of the method.

Graphical abstract: Gold-catalyzed enantioselective functionalization of indoles

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Article information


Submitted
16 Jun 2020
Accepted
14 Jul 2020
First published
23 Jul 2020

Org. Biomol. Chem., 2020,18, 6006-6017
Article type
Review Article

Gold-catalyzed enantioselective functionalization of indoles

P. Milcendeau, N. Sabat, A. Ferry and X. Guinchard, Org. Biomol. Chem., 2020, 18, 6006
DOI: 10.1039/D0OB01245A

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