Jump to main content
Jump to site search

Issue 8, 2020
Previous Article Next Article

Sequential conjugation methods based on triazole formation and related reactions using azides

Author affiliations

Abstract

The recent remarkable progress in azide chemistry has realized sequential conjugation methods with selective 1,2,3-triazole formation. On the basis of the diverse reactivities of azides and azidophiles, including terminal alkynes and cyclooctynes, various selective reactions to furnish triazoles and a wide range of platform molecules, such as diynes, diazides, triynes, and triazides, have been developed so far for bis- and tris(triazole) syntheses. This review highlights recent transformations involving selective triazole formation, allowing the efficient preparation of unsymmetric bis- and tris(triazole)s using diverse platform molecules.

Graphical abstract: Sequential conjugation methods based on triazole formation and related reactions using azides

Back to tab navigation

Article information


Submitted
19 Dec 2019
Accepted
23 Jan 2020
First published
23 Jan 2020

This article is Open Access

Org. Biomol. Chem., 2020,18, 1550-1562
Article type
Review Article

Sequential conjugation methods based on triazole formation and related reactions using azides

S. Yoshida, Org. Biomol. Chem., 2020, 18, 1550
DOI: 10.1039/C9OB02698C

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
  • For reproduction of material from PCCP:
    [Original citation] - Published by the PCCP Owner Societies.
  • For reproduction of material from PPS:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
  • For reproduction of material from all other RSC journals:
    [Original citation] - Published by The Royal Society of Chemistry.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.


Social activity

Search articles by author

Spotlight

Advertisements