CuFe2O4 nanoparticles catalyze the reaction of alkynes and nitrones for the synthesis of 2-azetidinones

Abstract

CuFe₂O₄ nanoparticles acted as a highly efficient heterogeneous catalyst in the reaction of alkynes and nitrones (Kinugasa reaction) for the synthesis of various 2-azetidinones. In all cases, the reactions proceeded conveniently under mild conditions with good-to-excellent yields and with a wide range of functional-group tolerance. The catalyst could be separated readily using an external magnet.