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Issue 34, 2020
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Halogen-bonded cocrystals of donepezil with perfluorinated diiodobenzenes

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Abstract

Donepezil, an active pharmaceutical ingredient with several different acceptor sites for halogen bonding has successfully been cocrystallized with two perfluorinated halogen bond donors. The prepared cocrystals provide insight into the halogen bonding potential of organic molecules with increased structural complexity.

Graphical abstract: Halogen-bonded cocrystals of donepezil with perfluorinated diiodobenzenes

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Supplementary files

Article information


Submitted
22 Jul 2020
Accepted
08 Aug 2020
First published
10 Aug 2020

CrystEngComm, 2020,22, 5573-5577
Article type
Communication

Halogen-bonded cocrystals of donepezil with perfluorinated diiodobenzenes

V. Nemec, T. Vitasović and D. Cinčić, CrystEngComm, 2020, 22, 5573 DOI: 10.1039/D0CE01065K

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