Issue 87, 2020

A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

Abstract

A cancer cell targeted fluorescent viscosity probe has been designed and synthesized to specifically visualise viscosity changes in biotin receptor (BiR) positive cells over biotin negative cells via dual-mode fluorescence imaging: fluorescence intensity mode and fluorescence lifetime mode.

Graphical abstract: A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

Supplementary files

Article information

Article type
Communication
Submitted
23 Jul 2020
Accepted
29 Sep 2020
First published
30 Sep 2020

Chem. Commun., 2020,56, 13351-13354

A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

M. Ren, Q. Xu, S. Wang, L. Liu and F. Kong, Chem. Commun., 2020, 56, 13351 DOI: 10.1039/D0CC05039C

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