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A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

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Abstract

A cancer cell targeted fluorescent viscosity probe has been designed and synthesized to specifically visualise viscosity changes in biotin receptor (BiR) positive cells over biotin negative cells via dual-mode fluorescence imaging: fluorescence intensity mode and fluorescence lifetime mode.

Graphical abstract: A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

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Article information


Submitted
23 Jul 2020
Accepted
29 Sep 2020
First published
30 Sep 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

M. Ren, Q. Xu, S. Wang, L. Liu and F. Kong, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC05039C

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