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Lipid based biocompatible ionic liquids: synthesis, characterization and biocompatibility evaluation

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Abstract

We report a new series of lipid-based biocompatible ionic liquids (LBILs) consisting of the long-chain phosphonium compound 1,2-dimyristoyl-sn-glycero-3-ethyl-phosphatidylcholine as the cation and the long-chain fatty acids stearic acid, oleic acid, or linoleic acid as anions. These materials were found to be completely miscible with many polar and nonpolar organic solvents as well as dispersible in water. These LBILs also exhibited excellent biocompatibility with an artificial three-dimensional human epidermis model.

Graphical abstract: Lipid based biocompatible ionic liquids: synthesis, characterization and biocompatibility evaluation

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Supplementary files

Article information


Submitted
29 Jun 2020
Accepted
06 Oct 2020
First published
07 Oct 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Lipid based biocompatible ionic liquids: synthesis, characterization and biocompatibility evaluation

S. Uddin, Md. R. Chowdhury, R. Wakabayashi, N. Kamiya, M. Moniruzzaman and M. Goto, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC04491A

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