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In situ detection of intracellular tissue transglutaminase based on aggregation-induced emission

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Abstract

Herein, a novel strategy for in situ imaging and real-time monitoring of intracellular tissue transglutaminase (TG2) is presented based on aggregation-induced emission (AIE). It has high sensitivity and specificity, minimal background signal and can also effectively distinguish different cell types (drug-resistant cancer cells, cancer cells and normal cells).

Graphical abstract: In situ detection of intracellular tissue transglutaminase based on aggregation-induced emission

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Article information


Submitted
10 May 2020
Accepted
26 Jun 2020
First published
29 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

In situ detection of intracellular tissue transglutaminase based on aggregation-induced emission

Y. Wu, Y. Gao, J. Su, Z. Chen and S. Liu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC03365K

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