A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(II) ion determination in living cells

Ziya Aydin; Bing Yan; Yibin Wei; Maolin Guo

doi:10.1039/D0CC01481H

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A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(ii) ion determination in living cells†

Ziya Aydin,

*^ab Bing Yan,^c Yibin Wei^c and Maolin Guo

*^bc

Author affiliations

* Corresponding authors

^a Vocational School of Technical Sciences, Karamanoğlu Mehmetbey University, Karaman 70100, Turkey
E-mail: ziyaaydin@kmu.edu.tr

^b Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01003, USA
E-mail: mguo@umassd.edu

^c Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth, 285 Old Westport Road, Dartmouth, MA 2747, USA

Abstract

A near-infrared ratiometric fluorescent probe CR-Ac based on a coumarin–benzopyrylium platform has been developed for selective detection of Cu²⁺. The cell imaging data revealed the capabilities of CR-Ac in monitoring the dynamic changes of subcellular Cu²⁺ and the quantification of Cu²⁺ levels in living cells.

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Article information

DOI: https://doi.org/10.1039/D0CC01481H
Article type: Communication
Submitted: 26 Feb 2020
Accepted: 23 Apr 2020
First published: 23 Apr 2020

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Chem. Commun., 2020,56, 6043-6046

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A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(II) ion determination in living cells

Z. Aydin, B. Yan, Y. Wei and M. Guo, Chem. Commun., 2020, 56, 6043 DOI: 10.1039/D0CC01481H

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Chemical Communications

A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(ii) ion determination in living cells†

Abstract

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A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(II) ion determination in living cells

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