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Tumor-targeted near-infrared fluorophore for fluorescence-guided phototherapy

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Abstract

A tumor-targeted near-infrared (NIR) fluorophore CA800SO3 was developed for fluorescence-guided phototherapy. This new type of NIR fluorophore showed high tumor targetability based on the structure-inherent targeting approach. This fluorophore generated sufficient hyperthermia and reactive oxygen species (ROS) simultaneously for synergistic cancer phototherapy, induced by an 808 nm laser irradiation.

Graphical abstract: Tumor-targeted near-infrared fluorophore for fluorescence-guided phototherapy

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Article information


Submitted
21 Feb 2020
Accepted
10 Mar 2020
First published
10 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Tumor-targeted near-infrared fluorophore for fluorescence-guided phototherapy

M. H. Park, G. Jo, E. J. Kim, J. S. Jung and H. Hyun, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01366H

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