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A route to virtually unlimited functionalization of water-soluble p-sulfonatocalix[4]arenes

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Abstract

The functionality of p-sulfonatocalix[4]arenes can be easily extended using the propargylation/CuAAC reaction sequence, which allows the introduction of up to four substituted triazole units to the narrow rims of the macrocycles while maintaining their cone shapes and water solubility and, thus, biomedical applicability.

Graphical abstract: A route to virtually unlimited functionalization of water-soluble p-sulfonatocalix[4]arenes

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Article information


Submitted
14 Feb 2020
Accepted
04 Mar 2020
First published
04 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

A route to virtually unlimited functionalization of water-soluble p-sulfonatocalix[4]arenes

A. Gorbunov, A. Iskandarova, K. Puchnin, V. Nenajdenko, V. Kovalev and I. Vatsouro, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01196G

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