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Chirality Sensing of Terpenes, Steroids, Amino Acids, Peptides and Drugs with Acyclic Cucurbit[n]urils and Molecular Tweezers

Abstract

Achiral chromophoric hosts, i.e. acyclic cucurbit[n]urils and molecular tweezers, were found to respond with characteristic Circular Dichroism (CD) spectra to the presence of micromolar concentra-tions of chiral hydrocarbons, terpenes, steroids, amino acids and their derivates, and drugs in water. In favourable cases, this allows for analyte identification or for reaction monitoring.

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Article information


Submitted
27 Jan 2020
Accepted
24 Feb 2020
First published
25 Feb 2020

This article is Open Access

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Chirality Sensing of Terpenes, Steroids, Amino Acids, Peptides and Drugs with Acyclic Cucurbit[n]urils and Molecular Tweezers

A. Prabodh, D. Bauer, S. Kubik, P. Rebmann, F. Klärner , T. Schrader, L. Delarue Bizzini, M. Mayor and F. Biedermann, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/D0CC00707B

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