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Issue 34, 2020
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A fluorescent nanobiosensor for the facile analysis of m6A RNA demethylase activity

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Abstract

RNA demethylase has recently been known to be associated with cancer development but its selective inhibitors as anti-cancer agents have rarely been investigated to date. Herein, we have developed a fluorescent nanobiosensor which enables efficient quantitative analysis of RNA demethylase ALKBH5 activity and shows a high potential for robust inhibitor screening.

Graphical abstract: A fluorescent nanobiosensor for the facile analysis of m6A RNA demethylase activity

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Supplementary files

Article information


Submitted
30 Dec 2019
Accepted
17 Mar 2020
First published
18 Mar 2020

Chem. Commun., 2020,56, 4716-4719
Article type
Communication

A fluorescent nanobiosensor for the facile analysis of m6A RNA demethylase activity

S. Yim, H. J. Cha, S. Park, Y. Yim, J. Woo and D. Min, Chem. Commun., 2020, 56, 4716
DOI: 10.1039/C9CC10054G

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